{"product_id":"abflo®-488-rabbit-anti-mouse-cd107b-monoclonal-antibody-a25930","title":"ABflo® 488 Rabbit anti-Mouse CD107b Monoclonal Antibody - A25930","description":"\u003cp\u003eABflo® 488 Rabbit anti-Mouse CD107b Monoclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 100T, 2 x 100T, 5 x 100T\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: A25930-100, A25930-200, A25930-500\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: Enables protein domain specific binding activity. Involved in several processes, including autophagosome maturation; protein stabilization; and protein targeting to lysosome involved in chaperone-mediated autophagy. Acts upstream of or within muscle cell cellular homeostasis. Located in late endosome membrane; lysosomal membrane; and phagocytic vesicle membrane. Is integral component of autophagosome membrane. Is expressed in central nervous system; egg cylinder; lung; and retina. Used to study Danon disease. Human ortholog(s) of this gene implicated in Danon disease and hypertrophic cardiomyopathy. Orthologous to human LAMP2 (lysosomal associated membrane protein 2).\u003c\/p\u003e\n\n\u003cp\u003eCategory: Monoclonal Antibodies\u003c\/p\u003e\n\n\u003cp\u003eApplication: FC\u003c\/p\u003e\n\n\u003cp\u003eCross Reactivity: Mouse\u003c\/p\u003e\n\n\u003cp\u003eProtein Weight: 46kDa Immunogen: Recombinant protein (or fragment).\u003c\/p\u003e\n\n\u003cp\u003eSpecies: Mouse\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 16784\u003c\/p\u003e\n\n\u003cp\u003eSWISS: P17047\u003c\/p\u003e\n\n\u003cp\u003eAlternate Names: Mac3; LGP-B; CD107b; Lamp-2; Lamp II; Lamp-2a; Lamp-2b; Lamp-2c\u003c\/p\u003e\n\n\u003cp\u003eSource: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003ePurity: Affinity purification\u003c\/p\u003e\n\n\u003cp\u003eStorage: Store at 2-8℃. Avoid freeze.|Buffer: PBS containing 0.2% BSA, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.\u003c\/p\u003e\n\n\u003cp\u003eRecommended Dilution: FC,5 μl per 10^6 cells in 100 μl volume\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Tags and Cell Markers Subcellular Markers Organelles LysosomeSignal Transduction Metabolism Energy MetabolismImmunology Secreted Molecules Other secreted moleculesCardiovascular Heart Autophagy AutophagosomeStem Cells Hematopoietic Progenitors Myeloid Myeloid ProgenitorStem Cells Hematopoietic Progenitors Myeloid Monocytic LineageMetabolism Pathways and Processes Metabolic signaling pathways Energy transfer pathways Energy MetabolismMetabolism Pathways and Processes Metabolism processes Autophagy and mitophagy AutophagosomeCancer Cell Death Autophagy AutophagosomeNeuroscience Processes\u003c\/p\u003e\n\n\u003cp\u003eNCBI Alias: Lamp2\u003c\/p\u003e\n\n\u003cp\u003eModifications: Unmodified\u003c\/p\u003e\n\n\u003cp\u003eConjugate: ABflo® 488. Ex:491nm. Em:516nm.\u003c\/p\u003e\n\n\u003cp\u003eClone Number Info: ARC63617\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ABclonal","offers":[{"title":"100T","offer_id":45189252972723,"sku":"A25930-100","price":109.2,"currency_code":"CAD","in_stock":true},{"title":"2 x 100T","offer_id":45189253005491,"sku":"A25930-200","price":179.2,"currency_code":"CAD","in_stock":true},{"title":"5 x 100T","offer_id":45189253038259,"sku":"A25930-500","price":319.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_bca97cf9-afe2-40b9-a83a-84af7f03e7d5.png?v=1766420327","url":"https:\/\/afsbio.com\/products\/abflo%c2%ae-488-rabbit-anti-mouse-cd107b-monoclonal-antibody-a25930","provider":"AFSBio Inc.","version":"1.0","type":"link"}