{"product_id":"abflo®-488-rabbit-anti-mouse-cd11b-monoclonal-antibody-a24094","title":"ABflo® 488 Rabbit anti-Mouse CD11b Monoclonal Antibody - A24094","description":"\u003cp\u003eABflo® 488 Rabbit anti-Mouse CD11b Monoclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 100T, 2 x 100T, 5 x 100T\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: A24094-100, A24094-200, A24094-500\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: Enables complement component C3b binding activity; heparan sulfate proteoglycan binding activity; and heparin binding activity. Contributes to cargo receptor activity. Involved in several processes, including central nervous system development; endocytosis; and positive regulation of neuron death. Acts upstream of or within several processes, including activated T cell proliferation; leukocyte migration; and microglia development. Located in external side of plasma membrane and nucleus. Is integral component of membrane. Part of integrin alphaM-beta2 complex. Is expressed in several structures, including central nervous system; heart; lymphatic vessel; thymus; and yolk sac. Human ortholog(s) of this gene implicated in lupus nephritis. Orthologous to human ITGAM (integrin subunit alpha M).\u003c\/p\u003e\n\n\u003cp\u003eCategory: Monoclonal Antibodies\u003c\/p\u003e\n\n\u003cp\u003eApplication: FC\u003c\/p\u003e\n\n\u003cp\u003eCross Reactivity: Mouse\u003c\/p\u003e\n\n\u003cp\u003eProtein Weight: 127kDa Immunogen: Recombinant protein (or fragment).\u003c\/p\u003e\n\n\u003cp\u003eSpecies: Mouse\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 16409\u003c\/p\u003e\n\n\u003cp\u003eSWISS: P05555\u003c\/p\u003e\n\n\u003cp\u003eAlternate Names: CR3; CR3A; MAC1; Cd11b; Ly-40; Mac-1; Mac-1a; CD11b\/CD18; F730045J24Rik\u003c\/p\u003e\n\n\u003cp\u003eSource: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003ePurity: Affinity purification\u003c\/p\u003e\n\n\u003cp\u003eStorage: Store at 2-8℃. Avoid freeze.|Buffer: PBS containing 0.2% BSA, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.\u003c\/p\u003e\n\n\u003cp\u003eRecommended Dilution: FC,5 μl per 10^6 cells in 100 μl volume\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Signal Transduction；Tags and Cell Markers；Neuroscience；Stem Cells\u003c\/p\u003e\n\n\u003cp\u003eNCBI Alias: Itgam\u003c\/p\u003e\n\n\u003cp\u003eModifications: Unmodified\u003c\/p\u003e\n\n\u003cp\u003eConjugate: ABflo® 488. Ex:491nm. Em:516nm.\u003c\/p\u003e\n\n\u003cp\u003eClone Number Info: ARC63899\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ABclonal","offers":[{"title":"100T","offer_id":45189206671539,"sku":"A24094-100","price":109.2,"currency_code":"CAD","in_stock":true},{"title":"2 x 100T","offer_id":45189206704307,"sku":"A24094-200","price":172.2,"currency_code":"CAD","in_stock":true},{"title":"5 x 100T","offer_id":45189206737075,"sku":"A24094-500","price":277.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_9da3542c-f434-4d67-8a46-3dd70fe7c06c.png?v=1766419548","url":"https:\/\/afsbio.com\/products\/abflo%c2%ae-488-rabbit-anti-mouse-cd11b-monoclonal-antibody-a24094","provider":"AFSBio Inc.","version":"1.0","type":"link"}