{"product_id":"abflo®-488-rat-anti-mouse-cd45r-b220-monoclonal-antibody-a27571","title":"ABflo® 488 Rat anti-Mouse CD45R\/B220 Monoclonal Antibody - A27571","description":"\u003cp\u003eABflo® 488 Rat anti-Mouse CD45R\/B220 Monoclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 100T, 2 x 100T, 5 x 100T\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: A27571-100, A27571-200, A27571-500\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: Enables several functions, including heparan sulfate proteoglycan binding activity; heparin binding activity; and protein tyrosine phosphatase activity. Involved in several processes, including lymphocyte differentiation; positive regulation of macromolecule metabolic process; and regulation of signal transduction. Acts upstream of or within several processes, including lymphocyte differentiation; positive regulation of lymphocyte activation; and regulation of protein phosphorylation. Located in external side of plasma membrane; focal adhesion; and membrane raft. Is expressed in several structures, including 3rd branchial arch; alimentary system; cardiovascular system; hemolymphoid system; and placenta. Used to study systemic lupus erythematosus. Human ortholog(s) of this gene implicated in hepatitis C; multiple sclerosis; severe combined immunodeficiency; and severe combined immunodeficiency, autosomal recessive, T cell-negative, B cell-positive, Nk cell-positive. Orthologous to human PTPRC (protein tyrosine phosphatase receptor type C).\u003c\/p\u003e\n\n\u003cp\u003eCategory: Monoclonal Antibodies\u003c\/p\u003e\n\n\u003cp\u003eApplication: FC\u003c\/p\u003e\n\n\u003cp\u003eCross Reactivity: Mouse\u003c\/p\u003e\n\n\u003cp\u003eProtein Weight: 130kDa\/140kDa\/144kDa Immunogen: Recombinant protein (or fragment).\u003c\/p\u003e\n\n\u003cp\u003eSpecies: Mouse\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 19264\u003c\/p\u003e\n\n\u003cp\u003eSWISS: P06800\u003c\/p\u003e\n\n\u003cp\u003eAlternate Names: loc; B220; Cd45; L-CA; Ly-5; T200; CD45R; Lyt-4\u003c\/p\u003e\n\n\u003cp\u003eSource: Rat\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003ePurity: Affinity purification\u003c\/p\u003e\n\n\u003cp\u003eStorage: Store at 2-8℃. Avoid freeze.|Buffer: PBS with 0.09% Sodium azide,0.2% BSA,pH7.3.\u003c\/p\u003e\n\n\u003cp\u003eRecommended Dilution: FC,5 μl per 10^6 cells in 100 μl volume\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Immunology, Adaptive Immunity, B Cells, CD\u003c\/p\u003e\n\n\u003cp\u003eNCBI Alias: PTPRC\u003c\/p\u003e\n\n\u003cp\u003eModifications: Unmodified\u003c\/p\u003e\n\n\u003cp\u003eConjugate: ABflo® 488. Ex:491nm. Em:516nm.\u003c\/p\u003e\n\n\u003cp\u003eClone Number Info: ATC10005\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ABclonal","offers":[{"title":"100T","offer_id":45189308219571,"sku":"A27571-100","price":67.2,"currency_code":"CAD","in_stock":true},{"title":"2 x 100T","offer_id":45189308252339,"sku":"A27571-200","price":123.2,"currency_code":"CAD","in_stock":true},{"title":"5 x 100T","offer_id":45189308285107,"sku":"A27571-500","price":221.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_07c57b53-7d58-4bac-a7aa-6dae40513e5f.png?v=1766421205","url":"https:\/\/afsbio.com\/products\/abflo%c2%ae-488-rat-anti-mouse-cd45r-b220-monoclonal-antibody-a27571","provider":"AFSBio Inc.","version":"1.0","type":"link"}