{"product_id":"abflo®-594-rabbit-anti-human-cd13-anpep-monoclonal-antibody-a24187","title":"ABflo® 594 Rabbit anti-Human CD13\/ANPEP Monoclonal Antibody - A24187","description":"\u003cp\u003eABflo® 594 Rabbit anti-Human CD13\/ANPEP Monoclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 100T, 2 x 100T, 5 x 100T\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: A24187-100, A24187-200, A24187-500\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: Aminopeptidase N is located in the small-intestinal and renal microvillar membrane, and also in other plasma membranes. In the small intestine aminopeptidase N plays a role in the final digestion of peptides generated from hydrolysis of proteins by gastric and pancreatic proteases. Its function in proximal tubular epithelial cells and other cell types is less clear. The large extracellular carboxyterminal domain contains a pentapeptide consensus sequence characteristic of members of the zinc-binding metalloproteinase superfamily. Sequence comparisons with known enzymes of this class showed that CD13 and aminopeptidase N are identical. The latter enzyme was thought to be involved in the metabolism of regulatory peptides by diverse cell types, including small intestinal and renal tubular epithelial cells, macrophages, granulocytes, and synaptic membranes from the CNS. This membrane-bound zinc metalloprotease is known to serve as a receptor for the HCoV-229E alphacoronavirus as well as other non-human coronaviruses. This gene has also been shown to promote angiogenesis, tumor growth, and metastasis and defects in this gene are associated with various types of leukemia and lymphoma.\u003c\/p\u003e\n\n\u003cp\u003eCategory: Monoclonal Antibodies\u003c\/p\u003e\n\n\u003cp\u003eApplication: FC\u003c\/p\u003e\n\n\u003cp\u003eCross Reactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eProtein Weight: 110kDa Immunogen: Recombinant protein (or fragment).\u003c\/p\u003e\n\n\u003cp\u003eSpecies: Human\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 290\u003c\/p\u003e\n\n\u003cp\u003eSWISS: P15144\u003c\/p\u003e\n\n\u003cp\u003eAlternate Names: APN; AP-M; AP-N; CD13; LAP1; P150; PEPN; hAPN; GP150\u003c\/p\u003e\n\n\u003cp\u003eSource: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003ePurity: Affinity purification\u003c\/p\u003e\n\n\u003cp\u003eStorage: Store at 2-8℃. Avoid freeze.|Buffer: PBS containing 0.2% BSA, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.\u003c\/p\u003e\n\n\u003cp\u003eRecommended Dilution: FC,5 μl per 10^6 cells in 100 μl volume\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Immunology Inflammation, CDs, Stem Cells, Hematopoietic Progenitors, Mesenchymal Stem Cells, Cardiovascular, Angiogenesis\u003c\/p\u003e\n\n\u003cp\u003eNCBI Alias: ANPEP\u003c\/p\u003e\n\n\u003cp\u003eModifications: Unmodified\u003c\/p\u003e\n\n\u003cp\u003eConjugate: ABflo® 594. Ex:588nm. Em:604nm.\u003c\/p\u003e\n\n\u003cp\u003eClone Number Info: ARC53703\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ABclonal","offers":[{"title":"100T","offer_id":45189205000371,"sku":"A24187-100","price":305.2,"currency_code":"CAD","in_stock":true},{"title":"2 x 100T","offer_id":45189205033139,"sku":"A24187-200","price":501.2,"currency_code":"CAD","in_stock":true},{"title":"5 x 100T","offer_id":45189205065907,"sku":"A24187-500","price":795.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_a26665e4-3aab-42bf-ae65-068a3a2d2aab.png?v=1766419517","url":"https:\/\/afsbio.com\/products\/abflo%c2%ae-594-rabbit-anti-human-cd13-anpep-monoclonal-antibody-a24187","provider":"AFSBio Inc.","version":"1.0","type":"link"}