{"product_id":"abflo®-594-rabbit-anti-human-cd177-monoclonal-antibody-a24403","title":"ABflo® 594 Rabbit anti-Human CD177 Monoclonal Antibody - A24403","description":"\u003cp\u003eABflo® 594 Rabbit anti-Human CD177 Monoclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 100T, 2 x 100T, 5 x 100T\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: A24403-100, A24403-200, A24403-500\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes a glycosyl-phosphatidylinositol (GPI)-linked cell surface glycoprotein that plays a role in neutrophil activation. The protein can bind platelet endothelial cell adhesion molecule-1 and function in neutrophil transmigration. Mutations in this gene are associated with myeloproliferative diseases. Over-expression of this gene has been found in patients with polycythemia rubra vera. Autoantibodies against the protein may result in pulmonary transfusion reactions, and it may be involved in Wegener's granulomatosis. A related pseudogene, which is adjacent to this gene on chromosome 19, has been identified.\u003c\/p\u003e \n\n\u003cp\u003eCategory: Monoclonal Antibodies\u003c\/p\u003e\n\n\u003cp\u003eApplication: FC\u003c\/p\u003e\n\n\u003cp\u003eCross Reactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eProtein Weight: 15kDa\/27kDa\/46kDa Immunogen: Recombinant protein (or fragment).\u003c\/p\u003e\n\n\u003cp\u003eSpecies: Human\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 57126\u003c\/p\u003e\n\n\u003cp\u003eSWISS: Q8N6Q3\u003c\/p\u003e\n\n\u003cp\u003eAlternate Names: CD177; HNA-2a; HNA2A; NB1; NB1 GP; PRV-1; PRV1; NB1GP; CD177 antigen\u003c\/p\u003e\n\n\u003cp\u003eSource: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003ePurity: Affinity purification\u003c\/p\u003e\n\n\u003cp\u003eStorage: Store at 2-8℃. Avoid freeze.|Buffer: PBS containing 0.2% BSA, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.\u003c\/p\u003e\n\n\u003cp\u003eRecommended Dilution: FC,5 μl per 10^6 cells in 100 μl volume\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Immunology and Inflammation, CD markers\u003c\/p\u003e\n\n\u003cp\u003eNCBI Alias: CD177\u003c\/p\u003e\n\n\u003cp\u003eModifications: Unmodified\u003c\/p\u003e\n\n\u003cp\u003eConjugate: ABflo® 594. Ex:588nm. Em:604nm.\u003c\/p\u003e\n\n\u003cp\u003eClone Number Info: ARC62693\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ABclonal","offers":[{"title":"100T","offer_id":45189219418291,"sku":"A24403-100","price":406.0,"currency_code":"CAD","in_stock":true},{"title":"2 x 100T","offer_id":45189219451059,"sku":"A24403-200","price":672.0,"currency_code":"CAD","in_stock":true},{"title":"5 x 100T","offer_id":45189219483827,"sku":"A24403-500","price":1075.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_e420f6f8-d434-42d4-939a-99390f41fa43.png?v=1766419761","url":"https:\/\/afsbio.com\/products\/abflo%c2%ae-594-rabbit-anti-human-cd177-monoclonal-antibody-a24403","provider":"AFSBio Inc.","version":"1.0","type":"link"}