{"product_id":"abflo®-647-rabbit-anti-human-il-10ra-cd210-monoclonal-antibody-a28197","title":"ABflo® 647 Rabbit anti-Human IL-10RA\/CD210 Monoclonal Antibody - A28197","description":"\u003cp\u003eABflo® 647 Rabbit anti-Human IL-10RA\/CD210 Monoclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 100T, 2 x 100T, 5 x 100T\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: A28197-100, A28197-200, A28197-500\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: The protein encoded by this gene is a receptor for interleukin 10. This protein is structurally related to interferon receptors. It has been shown to mediate the immunosuppressive signal of interleukin 10, and thus inhibits the synthesis of proinflammatory cytokines. This receptor is reported to promote survival of progenitor myeloid cells through the insulin receptor substrate-2\/PI 3-kinase\/AKT pathway. Activation of this receptor leads to tyrosine phosphorylation of JAK1 and TYK2 kinases. Two transcript variants, one protein-coding and the other not protein-coding, have been found for this gene.\u003c\/p\u003e\n\n\u003cp\u003eCategory: Monoclonal Antibodies\u003c\/p\u003e\n\n\u003cp\u003eApplication: FC\u003c\/p\u003e\n\n\u003cp\u003eCross Reactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eProtein Weight: 63 kDa Immunogen: Recombinant protein (or fragment).\u003c\/p\u003e\n\n\u003cp\u003eSpecies: Human\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 3587\u003c\/p\u003e\n\n\u003cp\u003eSWISS: Q13651\u003c\/p\u003e\n\n\u003cp\u003eAlternate Names: CD210; IL10R; CD210a; CDW210A; HIL-10R; IL-10R1\u003c\/p\u003e\n\n\u003cp\u003eSource: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003ePurity: Affinity purification\u003c\/p\u003e\n\n\u003cp\u003eStorage: Store at 2-8℃. Avoid freeze.|Buffer: PBS with 0.09% Sodium azide,0.2% BSA,pH7.3.\u003c\/p\u003e\n\n\u003cp\u003eRecommended Dilution: FC,5 μl per 10^6 cells in 100 μl volume\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Immunology Inflammation, CDs, Cytokines, Interleukins, Cell Intrinsic Innate Immunity Signaling Pathway\u003c\/p\u003e\n\n\u003cp\u003eNCBI Alias: IL10RA\u003c\/p\u003e\n\n\u003cp\u003eModifications: Unmodified\u003c\/p\u003e\n\n\u003cp\u003eConjugate: ABflo® 647. Ex:648nm. Em:664nm.\u003c\/p\u003e\n\n\u003cp\u003eClone Number Info: ARC63596\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ABclonal","offers":[{"title":"100T","offer_id":45189346623667,"sku":"A28197-100","price":333.2,"currency_code":"CAD","in_stock":true},{"title":"2 x 100T","offer_id":45189346656435,"sku":"A28197-200","price":571.2,"currency_code":"CAD","in_stock":true},{"title":"5 x 100T","offer_id":45189346689203,"sku":"A28197-500","price":1285.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_70264dab-b85c-4edb-b08c-519f90a09b4e.png?v=1766421848","url":"https:\/\/afsbio.com\/products\/abflo%c2%ae-647-rabbit-anti-human-il-10ra-cd210-monoclonal-antibody-a28197","provider":"AFSBio Inc.","version":"1.0","type":"link"}