{"product_id":"abflo®-647-rabbit-anti-human-nectin-1-cd111-monoclonal-antibody-a24989","title":"ABflo® 647 Rabbit anti-Human Nectin-1\/CD111 Monoclonal Antibody - A24989","description":"\u003cp\u003eABflo® 647 Rabbit anti-Human Nectin-1\/CD111 Monoclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 100T, 2 x 100T, 5 x 100T\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: A24989-100, A24989-200, A24989-500\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes an adhesion protein that plays a role in the organization of adherens junctions and tight junctions in epithelial and endothelial cells. The protein is a calcium(2+)-independent cell-cell adhesion molecule that belongs to the immunoglobulin superfamily and has 3 extracellular immunoglobulin-like loops, a single transmembrane domain (in some isoforms), and a cytoplasmic region. This protein acts as a receptor for glycoprotein D (gD) of herpes simplex viruses 1 and 2 (HSV-1, HSV-2), and pseudorabies virus (PRV) and mediates viral entry into epithelial and neuronal cells. Mutations in this gene cause cleft lip and palate\/ectodermal dysplasia 1 syndrome (CLPED1) as well as non-syndromic cleft lip with or without cleft palate (CL\/P). Alternative splicing results in multiple transcript variants encoding proteins with distinct C-termini.\u003c\/p\u003e\n\n\u003cp\u003eCategory: Monoclonal Antibodies\u003c\/p\u003e\n\n\u003cp\u003eApplication: FC\u003c\/p\u003e\n\n\u003cp\u003eCross Reactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eProtein Weight: 57kDa\/51kDa\/39kDa Immunogen: Recombinant protein (or fragment).\u003c\/p\u003e\n\n\u003cp\u003eSpecies: Human\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 5818\u003c\/p\u003e\n\n\u003cp\u003eSWISS: Q15223\u003c\/p\u003e\n\n\u003cp\u003eAlternate Names: ED4; PRR; HIgR; HV1S; HVEC; OFC7; PRR1; PVRR; CD111; PVRL1; PVRR1; SK-12; CLPED1; nectin-1\u003c\/p\u003e\n\n\u003cp\u003eSource: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003ePurity: Affinity purification\u003c\/p\u003e\n\n\u003cp\u003eStorage: Store at 2-8℃. Avoid freeze.|Buffer: PBS containing 0.2% BSA, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.\u003c\/p\u003e\n\n\u003cp\u003eRecommended Dilution: FC,5 μl per 10^6 cells in 100 μl volume\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Cell Biology Developmental Biology, Cell Adhesion, Immunology Inflammation, CDs, Neuroscience\u003c\/p\u003e\n\n\u003cp\u003eNCBI Alias: NECTIN1\u003c\/p\u003e\n\n\u003cp\u003eModifications: Unmodified\u003c\/p\u003e\n\n\u003cp\u003eConjugate: ABflo® 647. Ex:648nm. Em:664nm.\u003c\/p\u003e\n\n\u003cp\u003eClone Number Info: ARC65140\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ABclonal","offers":[{"title":"100T","offer_id":45189242650803,"sku":"A24989-100","price":406.0,"currency_code":"CAD","in_stock":true},{"title":"2 x 100T","offer_id":45189242683571,"sku":"A24989-200","price":672.0,"currency_code":"CAD","in_stock":true},{"title":"5 x 100T","offer_id":45189242716339,"sku":"A24989-500","price":1075.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_c0c77804-c24d-49c1-9a35-1f8f70f1d22b.png?v=1766420163","url":"https:\/\/afsbio.com\/products\/abflo%c2%ae-647-rabbit-anti-human-nectin-1-cd111-monoclonal-antibody-a24989","provider":"AFSBio Inc.","version":"1.0","type":"link"}