{"product_id":"abflo®-647-rabbit-anti-human-trka-monoclonal-antibody-a23974","title":"ABflo® 647 Rabbit anti-Human TrkA Monoclonal Antibody - A23974","description":"\u003cp\u003eABflo® 647 Rabbit anti-Human TrkA Monoclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 100T, 2 x 100T, 5 x 100T\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: A23974-100, A23974-200, A23974-500\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes a member of the neurotrophic tyrosine kinase receptor (NTKR) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. The presence of this kinase leads to cell differentiation and may play a role in specifying sensory neuron subtypes. Mutations in this gene have been associated with congenital insensitivity to pain, anhidrosis, self-mutilating behavior, mental retardation and cancer. Alternate transcriptional splice variants of this gene have been found, but only three have been characterized to date.\u003c\/p\u003e \n\n\u003cp\u003eCategory: Monoclonal Antibodies\u003c\/p\u003e\n\n\u003cp\u003eApplication: FC\u003c\/p\u003e\n\n\u003cp\u003eCross Reactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eProtein Weight: 77kDa\/83kDa\/86kDa\/87kDa Immunogen: Recombinant protein (or fragment).\u003c\/p\u003e\n\n\u003cp\u003eSpecies: Human\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 4914\u003c\/p\u003e\n\n\u003cp\u003eSWISS: P04629\u003c\/p\u003e\n\n\u003cp\u003eAlternate Names: NTRK1; MTC; TRK; TRK1; TRKA; Trk-A; p140-TrkA; neurotrophic receptor tyrosine kinase 1\u003c\/p\u003e\n\n\u003cp\u003eSource: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003ePurity: Affinity purification\u003c\/p\u003e\n\n\u003cp\u003eStorage: Store at 2-8℃. Avoid freeze.|Buffer: PBS containing 0.2% BSA, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.\u003c\/p\u003e\n\n\u003cp\u003eRecommended Dilution: FC,5 μl per 10^6 cells in 100 μl volume\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Cancer, Signal Transduction, Kinase, Tyrosine kinases, Cell Biology and Developmental Biology, Growth factor, Neuroscience\u003c\/p\u003e\n\n\u003cp\u003eNCBI Alias: NTRK1\u003c\/p\u003e\n\n\u003cp\u003eModifications: Unmodified\u003c\/p\u003e\n\n\u003cp\u003eConjugate: ABflo® 647. Ex:648nm. Em:664nm.\u003c\/p\u003e\n\n\u003cp\u003eClone Number Info: ARC61412\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ABclonal","offers":[{"title":"100T","offer_id":45189195464883,"sku":"A23974-100","price":406.0,"currency_code":"CAD","in_stock":true},{"title":"2 x 100T","offer_id":45189195497651,"sku":"A23974-200","price":672.0,"currency_code":"CAD","in_stock":true},{"title":"5 x 100T","offer_id":45189195530419,"sku":"A23974-500","price":1075.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_1ca71644-365d-436f-badb-3247b4d6e3bb.png?v=1766419364","url":"https:\/\/afsbio.com\/products\/abflo%c2%ae-647-rabbit-anti-human-trka-monoclonal-antibody-a23974","provider":"AFSBio Inc.","version":"1.0","type":"link"}