{"product_id":"abflo®-647-rabbit-anti-mouse-cd105-endoglin-monoclonal-antibody-a25378","title":"ABflo® 647 Rabbit anti-Mouse CD105\/Endoglin Monoclonal Antibody - A25378","description":"\u003cp\u003eABflo® 647 Rabbit anti-Mouse CD105\/Endoglin Monoclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 100T, 2 x 100T, 5 x 100T\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: A25378-100, A25378-200, A25378-500\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: Enables protein homodimerization activity and transforming growth factor beta binding activity. Involved in several processes, including circulatory system development; positive regulation of cell differentiation; and regulation of gene expression. Acts upstream of or within circulatory system development and positive regulation of angiogenesis. Located in endothelial microparticle. Is expressed in several structures, including brain; cardiovascular system; extraembryonic vascular system; and lung. Used to study arteriovenous malformations of the brain and hereditary hemorrhagic telangiectasia. Human ortholog(s) of this gene implicated in arteriovenous malformation; arteriovenous malformations of the brain; breast cancer; hereditary hemorrhagic telangiectasia; and intracranial aneurysm. Orthologous to human ENG (endoglin).\u003c\/p\u003e\n\n\u003cp\u003eCategory: Monoclonal Antibodies\u003c\/p\u003e\n\n\u003cp\u003eApplication: FC\u003c\/p\u003e\n\n\u003cp\u003eCross Reactivity: Mouse\u003c\/p\u003e\n\n\u003cp\u003eProtein Weight: 70kDa Immunogen: Recombinant protein (or fragment).\u003c\/p\u003e\n\n\u003cp\u003eSpecies: Mouse\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 13805\u003c\/p\u003e\n\n\u003cp\u003eSWISS: Q63961\u003c\/p\u003e\n\n\u003cp\u003eAlternate Names: Endo; CD105; S-endoglin\u003c\/p\u003e\n\n\u003cp\u003eSource: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003ePurity: Affinity purification\u003c\/p\u003e\n\n\u003cp\u003eStorage: Store at 2-8℃. Avoid freeze.|Buffer: PBS containing 0.2% BSA, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.\u003c\/p\u003e\n\n\u003cp\u003eRecommended Dilution: FC,5 μl per 10^6 cells in 100 μl volume\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Cancer, Tumor biomarkers, Immunology Inflammation, CDs, Stem Cells, Mesenchymal Stem Cells, Cardiovascular\u003c\/p\u003e\n\n\u003cp\u003eNCBI Alias: Eng\u003c\/p\u003e\n\n\u003cp\u003eModifications: Unmodified\u003c\/p\u003e\n\n\u003cp\u003eConjugate: ABflo® 647. Ex:648nm. Em:664nm.\u003c\/p\u003e\n\n\u003cp\u003eClone Number Info: ARC66234\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ABclonal","offers":[{"title":"100T","offer_id":45189236883635,"sku":"A25378-100","price":95.2,"currency_code":"CAD","in_stock":true},{"title":"2 x 100T","offer_id":45189236916403,"sku":"A25378-200","price":165.2,"currency_code":"CAD","in_stock":true},{"title":"5 x 100T","offer_id":45189236949171,"sku":"A25378-500","price":263.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_226dac61-80a9-4ff4-b396-b8c96a3542d1.png?v=1766420052","url":"https:\/\/afsbio.com\/products\/abflo%c2%ae-647-rabbit-anti-mouse-cd105-endoglin-monoclonal-antibody-a25378","provider":"AFSBio Inc.","version":"1.0","type":"link"}