{"product_id":"abflo®-647-rabbit-anti-mouse-rank-cd265-monoclonal-antibody-a27179","title":"ABflo® 647 Rabbit anti-Mouse RANK\/CD265 Monoclonal Antibody - A27179","description":"\u003cp\u003eABflo® 647 Rabbit anti-Mouse RANK\/CD265 Monoclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 100T, 2 x 100T, 5 x 100T\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: A27179-100, A27179-200, A27179-500\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: Enables tumor necrosis factor-activated receptor activity. Involved in several processes, including circadian temperature homeostasis; positive regulation of fever generation by positive regulation of prostaglandin secretion; and tumor necrosis factor-mediated signaling pathway. Acts upstream of or within several processes, including hematopoietic or lymphoid organ development; mammary gland alveolus development; and positive regulation of bone resorption. Located in cell surface. Is expressed in bladder and lymphatic system. Human ortholog(s) of this gene implicated in Paget's disease of bone; autosomal recessive osteopetrosis 7; bone development disease; familial expansile osteolysis; and osteoporosis. Orthologous to human TNFRSF11A (TNF receptor superfamily member 11a).\u003c\/p\u003e\n\n\u003cp\u003eCategory: Monoclonal Antibodies\u003c\/p\u003e\n\n\u003cp\u003eApplication: FC\u003c\/p\u003e\n\n\u003cp\u003eCross Reactivity: Mouse\u003c\/p\u003e\n\n\u003cp\u003eProtein Weight: 67kDa Immunogen: Recombinant protein (or fragment).\u003c\/p\u003e\n\n\u003cp\u003eSpecies: Mouse\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 21934\u003c\/p\u003e\n\n\u003cp\u003eSWISS: O35305\u003c\/p\u003e\n\n\u003cp\u003eAlternate Names: OFE; ODFR; Rank; Ly109; mRANK; TRANCE-R\u003c\/p\u003e\n\n\u003cp\u003eSource: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003ePurity: Affinity purification\u003c\/p\u003e\n\n\u003cp\u003eStorage: Store at 2-8℃. Avoid freeze.|Buffer: PBS containing 0.2% BSA, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.\u003c\/p\u003e\n\n\u003cp\u003eRecommended Dilution: FC,5 μl per 10^6 cells in 100 μl volume\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Immunology Innate Immunity Cytokines TNF SuperfamilySignal Transduction Adapters TransmembraneSignal Transduction Growth Factors\/Hormones TNFSignal Transduction Cytoskeleton \/ ECM Extracellular Matrix Structures BoneCardiovascular Atherosclerosis Vascular Inflammation Inflammatory mediatorsNeuroscience Development\u003c\/p\u003e\n\n\u003cp\u003eNCBI Alias: Tnfrsf11a\u003c\/p\u003e\n\n\u003cp\u003eModifications: Unmodified\u003c\/p\u003e\n\n\u003cp\u003eConjugate: ABflo® 647. Ex:648nm. Em:664nm.\u003c\/p\u003e\n\n\u003cp\u003eClone Number Info: ARC65571\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ABclonal","offers":[{"title":"100T","offer_id":45189318082739,"sku":"A27179-100","price":333.2,"currency_code":"CAD","in_stock":true},{"title":"2 x 100T","offer_id":45189318115507,"sku":"A27179-200","price":571.2,"currency_code":"CAD","in_stock":true},{"title":"5 x 100T","offer_id":45189318148275,"sku":"A27179-500","price":1047.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_e3151280-186b-4f07-9995-5baa8460e373.png?v=1766421362","url":"https:\/\/afsbio.com\/products\/abflo%c2%ae-647-rabbit-anti-mouse-rank-cd265-monoclonal-antibody-a27179","provider":"AFSBio Inc.","version":"1.0","type":"link"}