{"product_id":"abflo®-700-rabbit-anti-mouse-cd11b-monoclonal-antibody-a26230","title":"ABflo® 700 Rabbit anti-Mouse CD11b Monoclonal Antibody - A26230","description":"\u003cp\u003eABflo® 700 Rabbit anti-Mouse CD11b Monoclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 100T, 2 x 100T, 5 x 100T\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: A26230-100, A26230-200, A26230-500\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: Enables complement component C3b binding activity; heparan sulfate proteoglycan binding activity; and heparin binding activity. Contributes to cargo receptor activity. Involved in several processes, including central nervous system development; endocytosis; and positive regulation of neuron death. Acts upstream of or within several processes, including activated T cell proliferation; leukocyte migration; and microglia development. Located in external side of plasma membrane and nucleus. Is integral component of membrane. Part of integrin alphaM-beta2 complex. Is expressed in several structures, including central nervous system; heart; lymphatic vessel; thymus; and yolk sac. Human ortholog(s) of this gene implicated in lupus nephritis. Orthologous to human ITGAM (integrin subunit alpha M).\u003c\/p\u003e\n\n\u003cp\u003eCategory: Monoclonal Antibodies\u003c\/p\u003e\n\n\u003cp\u003eApplication: FC\u003c\/p\u003e\n\n\u003cp\u003eCross Reactivity: Mouse\u003c\/p\u003e\n\n\u003cp\u003eProtein Weight: 127kDa Immunogen: Recombinant protein (or fragment).\u003c\/p\u003e\n\n\u003cp\u003eSpecies: Mouse\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 16409\u003c\/p\u003e\n\n\u003cp\u003eSWISS: P05555\u003c\/p\u003e\n\n\u003cp\u003eAlternate Names: CR3; CR3A; MAC1; Cd11b; Ly-40; Mac-1; Mac-1a; CD11b\/CD18; F730045J24Rik\u003c\/p\u003e\n\n\u003cp\u003eSource: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003ePurity: Affinity purification\u003c\/p\u003e\n\n\u003cp\u003eStorage: Store at 2-8℃. Avoid freeze.|Buffer: PBS with 0.09% Sodium azide,0.2% BSA,pH7.3.\u003c\/p\u003e\n\n\u003cp\u003eRecommended Dilution: FC,5 μl per 10^6 cells in 100 μl volume\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Signal Transduction;Tags and Cell Markers;Neuroscience;Stem Cells\u003c\/p\u003e\n\n\u003cp\u003eNCBI Alias: Itgam\u003c\/p\u003e\n\n\u003cp\u003eModifications: Unmodified\u003c\/p\u003e\n\n\u003cp\u003eConjugate: ABflo® 700. Ex:690nm. Em:713nm.\u003c\/p\u003e\n\n\u003cp\u003eClone Number Info: ARC63899\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ABclonal","offers":[{"title":"100T","offer_id":45189270765747,"sku":"A26230-100","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"2 x 100T","offer_id":45189270798515,"sku":"A26230-200","price":249.2,"currency_code":"CAD","in_stock":true},{"title":"5 x 100T","offer_id":45189270831283,"sku":"A26230-500","price":445.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_911e442d-316a-4df1-9915-e5ea6fc34e03.png?v=1766420609","url":"https:\/\/afsbio.com\/products\/abflo%c2%ae-700-rabbit-anti-mouse-cd11b-monoclonal-antibody-a26230","provider":"AFSBio Inc.","version":"1.0","type":"link"}