{"product_id":"acadl-rabbit-polyclonal-antibody-es18504","title":"ACADL Rabbit Polyclonal Antibody - ES18504","description":"\u003cp\u003eACADL Rabbit Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: ES18504-50, ES18504-100\u003c\/p\u003e\n\n\u003cp\u003eLead times: 1-2 weeks, if manufacturer has product in stock\u003c\/p\u003e\n\n\u003cp\u003eManufacturer\/Ship Location: China\u003c\/p\u003e\n\n\u003cp\u003eBackground: The protein encoded by this gene belongs to the acyl-CoA dehydrogenase family, which is a family of mitochondrial flavoenzymes involved in fatty acid and branched chain amino-acid metabolism. This protein is one of the four enzymes that catalyze the initial step of mitochondrial beta-oxidation of straight-chain fatty acid. Defects in this gene are the cause of long-chain acyl-CoA dehydrogenase (LCAD) deficiency, leading to nonketotic hypoglycemia. [provided by RefSeq, Jul 2008],\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Synthesized peptide derived from human ACADL AA range: 258-308\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eTarget: ACADL\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: This antibody detects endogenous levels of ACADL at Human\/Mouse\/Rat\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB 1：500-2000\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml,\u003c\/p\u003e\n\n\u003cp\u003eFormlation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 47kD\u003c\/p\u003e\n\n\u003cp\u003eFields: Fatty acid degradation, Metabolic pathways, Fatty acid metabolism, PPAR signaling pathway\u003c\/p\u003e\n\n\u003cp\u003eFunction: Catalytic Activity: Acyl-CoA + acceptor = 2,3-dehydroacyl-CoA + reduced acceptor\u003cbr\u003e\nCofactor: FAD\u003cbr\u003e\nDisease: Impaired ACADL activity results in non-ketotic hypoglycemia, hypotonia, muscle weakness and episodes of cardiorespiratory arrest associated with fasting [MIM: 201460]\u003cbr\u003e\nMiscellaneous: A number of straight-chain acyl-CoA dehydrogenases of different substrate specificities are present in mammalian tissues\u003cbr\u003e\nPathway: Lipid metabolism, mitochondrial fatty acid beta-oxidation\u003cbr\u003e\nSimilarity: Belongs to the acyl-CoA dehydrogenase family\u003cbr\u003e\nSubunit: Homotetramer\u003c\/p\u003e\n\n\n\u003cp\u003eSubcellular Location: Mitochondrion matrix\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: -20°C\/1 year\u003c\/p\u003e\n\n\u003cp\u003eGene Name: ACADL\u003c\/p\u003e\n\n\u003cp\u003eProtein Name: ACADL\u003c\/p\u003e\n\n\u003cp\u003eMouse Gene ID: 11363\u003c\/p\u003e\n\n\u003cp\u003eMouse SwissProt Number: P51174\u003c\/p\u003e\n\n\u003cp\u003eRat Gene ID: 25287\u003c\/p\u003e\n\n\u003cp\u003eRat SwissProt Number: P15650\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ELK Biotechnology","offers":[{"title":"50μL","offer_id":46315854397619,"sku":"ES18504-50","price":186.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":46315854430387,"sku":"ES18504-100","price":372.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/elk_antibodies.jpg?v=1793190497","url":"https:\/\/afsbio.com\/products\/acadl-rabbit-polyclonal-antibody-es18504","provider":"AFSBio Inc.","version":"1.0","type":"link"}