{"product_id":"ace2-polyclonal-antibody-bt-ap00153","title":"ACE2 Polyclonal Antibody - BT-AP00153","description":"\u003cp\u003eACE2 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP00153-20, BT-AP00153-50, BT-AP00153-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: The protein encoded by ACE2 (angiotensin I converting enzyme 2)belongs to the angiotensin-converting enzyme family of dipeptidyl carboxydipeptidases and has considerable homology to human angiotensin 1 converting enzyme. This secreted protein catalyzes the cleavage of angiotensin I into angiotensin 1-9, and angiotensin II into the vasodilator angiotensin 1-7. The organ- and cell-specific expression of ACE2 suggests that it may play a role in the regulation of cardiovascular and renal function, as well as fertility. In addition, the encoded protein is a functional receptor for the spike glycoprotein of the human coronaviruses SARS and HCoV-NL63.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Microbiology; Cell Biology\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: ACE2\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: ACE2 Antibody\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 92463\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: Q9BYF1; Mouse: Q8R0I0\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: ACE2; Angiotensin-converting enzyme 2; ACE-related carboxypeptidase; Angiotensin-converting enzyme homolog; ACEH; Metalloprotease MPROT15\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 59272; Mouse: 70008\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45240087609523,"sku":"BT-AP00153-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45240087642291,"sku":"BT-AP00153-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45240087675059,"sku":"BT-AP00153-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_e8444639-1520-4db8-ae7f-807cad4f606a.png?v=1769403257","url":"https:\/\/afsbio.com\/products\/ace2-polyclonal-antibody-bt-ap00153","provider":"AFSBio Inc.","version":"1.0","type":"link"}