{"product_id":"acetyl-dnmt1-k1127-k1129-k1131-k1133-polyclonal-antibody-bs7948","title":"Acetyl-DNMT1-K1127\/K1129\/K1131\/K1133 Polyclonal Antibody-BS7948","description":"\u003cp\u003eAcetyl-DNMT1-K1127\/K1129\/K1131\/K1133 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50µl, 100µl\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BS7948-50, BS7948-100\u003c\/p\u003e\n\n\u003cp\u003eProduct: 1mg\/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2\u003c\/p\u003e\n\n\u003cp\u003eSwiss-Prot: P26358\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eApplications: IHC, IF\/ICC\u003c\/p\u003e\n\n\u003cp\u003eAll Applications: IHC,1:50 - 1:100 | IF\/ICC,1:50 - 1:100\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes an enzyme that transfers methyl groups to cytosine nucleotides of genomic DNA. This protein is the major enzyme responsible for maintaining methylation patterns following DNA replication and shows a preference for hemi-methylated DNA. Methylation of DNA is an important component of mammalian epigenetic gene regulation. Aberrant methylation patterns are found in human tumors and associated with developmental abnormalities. Variation in this gene has been associated with cerebellar ataxia, deafness, and narcolepsy, and neuropathy, hereditary sensory, type IE. Alternative splicing results in multiple transcript variants.\u003c\/p\u003e \n\n\u003cp\u003ePurification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is \u0026gt; 95% (by SDS-PAGE).\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: Acetylated Antibodies\u003c\/p\u003e\n\n\u003cp\u003eNote: For research use only, not for use in diagnostic procedure.\u003c\/p\u003e\n\n\u003cp\u003eExtra Notes: Immunofluorescence analysis of C6 cells using Acetyl-DNMT1-K1127\/K1129\/K1131\/K1133 antibody at dilution of 1:100. Blue: DAPI for nuclear staining.\u003c\/p\u003e\n\n\u003cp\u003eAlternative Name: ADCADN; AIM; CXXC9; DNMT; HSN1E; MCMT; m.HsaI; DNMT1\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: A synthetic acetylated peptide around K1127 \u0026amp; K1129 \u0026amp; K1131 \u0026amp; K1133 of human DNMT1(NP_001124295.1).\u003c\/p\u003e\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eModification: Unmodified\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"50µl","offer_id":42929125294259,"sku":"BS7948-50","price":334.88,"currency_code":"CAD","in_stock":true},{"title":"100µl","offer_id":42929125327027,"sku":"BS7948-100","price":576.38,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_1baaac13-1492-477b-ba55-6e3a80525f40.jpg?v=1704197858","url":"https:\/\/afsbio.com\/products\/acetyl-dnmt1-k1127-k1129-k1131-k1133-polyclonal-antibody-bs7948","provider":"AFSBio Inc.","version":"1.0","type":"link"}