{"product_id":"acetyl-histone-h3-k18-rabbit-pab-a7257","title":"Acetyl-Histone H3-K18 Rabbit pAb - A7257","description":"\u003cp\u003eAcetyl-Histone H3-K18 Rabbit pAb\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: A7257-20, A7257-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H3 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the small histone gene cluster on chromosome 6p22-p21.3.\u003c\/p\u003e\n\n\u003cp\u003eCategory: Acetylated Antibodies\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, DB, IHC-P, IF\/ICC, ELISA, ChIP\u003c\/p\u003e\n\n\u003cp\u003eCross-reactivity: Human, Mouse, Rat, Other (Wide Range Predicted)\u003c\/p\u003e \n\n\u003cp\u003eProtein Weight: 15kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved Molecular Weight: 17kDa\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Synthetic peptide .\u003c\/p\u003e\n\n\u003cp\u003eSpecies: Human\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 8290\/8350\u003c\/p\u003e\n\n\u003cp\u003eSWISS: Q16695\/P68431\u003c\/p\u003e\n\n\u003cp\u003eAlternate Names: H3\/j; H3C1; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3FJ; H3C10; H3C11; HIST1H3J; Acetyl-Histone H3-K18\u003c\/p\u003e\n\n\u003cp\u003eSource: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003ePurity: Affinity purification\u003c\/p\u003e\n\n\u003cp\u003eStorage: Store at -20℃. Avoid freeze \/ thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis),  pH 7.3.\u003c\/p\u003e\n\n\u003cp\u003eRecommended Dilutions: WB, 1:500 - 1:1000 DB, 1:500 - 1:1000 IHC-P, 1:50 - 1:200 IF\/ICC, 1:50 - 1:200 ELISA, Recommended starting concentration is 1 μg\/mL. Please optimize the concentration based on your specific assay requirements. ChIP, 5μg antibody for 5μg-10μg of Chromatin\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Epigenetics \u0026amp; Nuclear Signaling, Epigenetic Modifications, Acetylation, Epigenetics \u0026amp; Nuclear Signaling, Epigenetic Modifications, Acetylation, Epigenetics \u0026amp; Nuclear Signaling, Epigenetic Modifications, Acetylation.\u003c\/p\u003e\n\n\u003cp\u003eNCBI Alias: H3C12\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ABclonal","offers":[{"title":"20uL","offer_id":45190028198067,"sku":"A7257-20","price":179.2,"currency_code":"CAD","in_stock":true},{"title":"100uL","offer_id":45190028230835,"sku":"A7257-100","price":515.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_d9a27850-9b10-4b5c-8706-e523fdf0d48b.png?v=1766440233","url":"https:\/\/afsbio.com\/products\/acetyl-histone-h3-k18-rabbit-pab-a7257","provider":"AFSBio Inc.","version":"1.0","type":"link"}