{"product_id":"acetyl-p53-lys370-monoclonal-antibody-mb10486","title":"Acetyl-p53 (Lys370) Monoclonal Antibody-MB10486","description":"\u003cp\u003eAcetyl-p53 (Lys370) Monoclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50µl, 100µl\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: MB10486-50, MB10486-100\u003c\/p\u003e\n\n\u003cp\u003eProduct: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA\u003c\/p\u003e\n\n\u003cp\u003eSwiss-Prot: P04637\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ICC\/IF, IP,\u003c\/p\u003e \n\n\u003cp\u003eAll Applications: WB: 1\/500-1\/1000  IF: 1\/50-1\/200  IP: 1\/20\u003c\/p\u003e  \n\n\u003cp\u003eBackground: Tumor protein p53, a nuclear protein, plays an essential role in the regulation of cell cycle, specifically in the transition from G0 to G1. It is found in very low levels in normal cells, however, in a variety of transformed cell lines, it is expressed in high amounts, and believed to contribute to transformation and malignancy. p53 is a DNA-binding protein containing DNA-binding, oligomerization and transcription activation domains.\u003c\/p\u003e\n\n\u003cp\u003ePurification and Purity: Affinity Purified\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: IgG\u003c\/p\u003e\n\n\u003cp\u003eBioworld Molecular Weight: Calculated MW: 44 kDa; Observed MW: 53 kDa\u003c\/p\u003e\n\n\u003cp\u003eNote: For research use only, not for use in diagnostic procedure.\u003c\/p\u003e\n\n\u003cp\u003eExtra Notes: Immunocytochemistry analysis of Acetyl-p53 in 3T3 using Acetyl-p53 antibody, and DAPI., Western blot analysis of Acetyl-p53 in Hela, Hela+TSA, 3T3, 3T3+TSA lysates using Acetyl-p53 antibody., Western blot analysis of Acetyl-p53 in rat Brain lysates using Acetyl-p53 antibody\u003c\/p\u003e\n\n\u003cp\u003eAlternative Name: P53; BCC7; LFS1; TRP53\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: A synthetic acetyl-peptide corresponding to residues surrounding Lys370 of human p53\u003c\/p\u003e\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eModification: Acetylated\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"50µl","offer_id":43004729622707,"sku":"MB10486-50","price":424.94,"currency_code":"CAD","in_stock":true},{"title":"100µl","offer_id":43004729655475,"sku":"MB10486-100","price":655.54,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_63299d7c-1adb-406f-aa67-c8dbeb1196f2.jpg?v=1706444824","url":"https:\/\/afsbio.com\/products\/acetyl-p53-lys370-monoclonal-antibody-mb10486","provider":"AFSBio Inc.","version":"1.0","type":"link"}