{"product_id":"achb4-polyclonal-antibody-bt-ap14085","title":"ACHB4 Polyclonal Antibody - BT-AP14085","description":"\u003cp\u003eACHB4 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP14085-20, BT-AP14085-50, BT-AP14085-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: After binding acetylcholine| the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.|Belongs to the ligand-gated ionic channel (TC 1.A.9) family.|subunit:Neuronal AChR is composed of two different types of subunits: alpha and beta. Beta-4 subunit can be combined to alpha-2| alpha-3 or alpha-4 to give rise to functional receptors. Interacts with RIC3; which is required for proper folding and assembly.|\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Neuroscience\u003c\/p\u003e \n\n\u003cp\u003eTarget Protein: CHRNB4\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Rat, Mouse\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: Neuronal acetylcholine receptor subunit beta-4\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: P30926; Mouse: Q8R493; Rat: P12392\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: Neuronal acetylcholine receptor subunit beta-4\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 1143\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45239039819955,"sku":"BT-AP14085-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45239039852723,"sku":"BT-AP14085-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45239039885491,"sku":"BT-AP14085-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_724151ef-584a-4d88-99e0-723c5ba6a4e2.png?v=1769388281","url":"https:\/\/afsbio.com\/products\/achb4-polyclonal-antibody-bt-ap14085","provider":"AFSBio Inc.","version":"1.0","type":"link"}