{"product_id":"ache-polyclonal-antibody-bt-ap00167","title":"AChE Polyclonal Antibody - BT-AP00167","description":"\u003cp\u003eAChE Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP00167-20, BT-AP00167-50, BT-AP00167-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: Acetylcholinesterase hydrolyzes the neurotransmitter, acetylcholine at neuromuscular junctions and brain cholinergic synapses, and thus terminates signal transmission. It is also found on the red blood cell membranes, where it constitutes the Yt blood group antigen. Acetylcholinesterase exists in multiple molecular forms which possess similar catalytic properties, but differ in their oligomeric assembly and mode of cell attachment to the cell surface. It is encoded by the single ACHE gene, and the structural diversity in the gene products arises from alternative mRNA splicing, and post-translational associations of catalytic and structural subunits. The major form of acetylcholinesterase found in brain, muscle and other tissues is the hydrophilic species, which forms disulfide-linked oligomers with collagenous, or lipid-containing structural subunits. The other, alternatively spliced form, expressed primarily in the erythroid tissues, differs at the C-terminal end, and contains a cleavable hydrophobic peptide with a GPI-anchor site. It associates with the membranes through the phosphoinositide (PI) moieties added post-translationally.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Neuroscience; Cardiovascular\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: ACHE\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: AChE Antibody\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 67796\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: P22303; Mouse: P21836; Rat: P37136\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: ACHE; Acetylcholinesterase; AChE\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 43; Mouse: 11423; Rat: 83817\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45240088297651,"sku":"BT-AP00167-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45240088330419,"sku":"BT-AP00167-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45240088363187,"sku":"BT-AP00167-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_c916b8d9-49ac-4638-8198-7e74e2e58d1c.png?v=1769403266","url":"https:\/\/afsbio.com\/products\/ache-polyclonal-antibody-bt-ap00167","provider":"AFSBio Inc.","version":"1.0","type":"link"}