{"product_id":"acl6b-polyclonal-antibody-bt-ap14102","title":"ACL6B Polyclonal Antibody - BT-AP14102","description":"\u003cp\u003eACL6B Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP14102-20, BT-AP14102-50, BT-AP14102-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: The protein encoded by this gene is a member of a family of actin-related proteins (ARPs) which share significant amino acid sequence identity to conventional actins. Both actins and ARPs have an actin fold| which is an ATP-binding cleft| as a common feature. The ARPs are involved in diverse cellular processes| including vesicular transport| spindle orientation| nuclear migration and chromatin remodeling. This gene encodes a subunit of the BAF (BRG1\/brm-associated factor) complex in mammals| which is functionally related to SWI\/SNF complex in S. cerevisiae and Drosophila; the latter is thought to facilitate transcriptional activation of specific genes by antagonizing chromatin-mediated transcriptional repression. This subunit may be involved in the regulation of genes by structural modulation of their chromatin| specifically in the brain. Alternative splicing results in multiple transcript variants.\u003c\/p\u003e \n\n\u003cp\u003eResearch Areas: Epigenetics and nuclear signaling; Neuroscience; Stem cells\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: ACTL6B\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: Actin-like protein 6B\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: O94805; Mouse: Q99MR0; Rat: P86173\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: Actin-like protein 6B;53 kDa BRG1-associated factor B;Actin-related protein Baf53b;ArpNalpha;BRG1-associated factor 53B;BAF53B\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 51412\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45239040245939,"sku":"BT-AP14102-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45239040278707,"sku":"BT-AP14102-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45239040311475,"sku":"BT-AP14102-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_79781f85-c526-4251-9215-106f1c6d09dc.png?v=1769388289","url":"https:\/\/afsbio.com\/products\/acl6b-polyclonal-antibody-bt-ap14102","provider":"AFSBio Inc.","version":"1.0","type":"link"}