{"product_id":"aco11-polyclonal-antibody-bt-ap06003","title":"ACO11 Polyclonal Antibody - BT-AP06003","description":"\u003cp\u003eACO11 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP06003-20, BT-AP06003-50, BT-AP06003-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes a member of the acyl-CoA thioesterase family which catalyse the conversion of activated fatty acids to the corresponding non-esterified fatty acid and coenzyme A. Expression of a mouse homolog in brown adipose tissue is induced by low temperatures and repressed by warm temperatures. Higher levels of expression of the mouse homolog has been found in obesity-resistant mice compared with obesity-prone mice| suggesting a role of acyl-CoA thioesterase 11 in obesity. Alternative splicing results in transcript variants.\u003c\/p\u003e \n\n\u003cp\u003eResearch Areas: Cardiovascular; Metabolism; Signal transduction\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: ACOT11\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: Acyl-coenzyme A thioesterase 11\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: Q8WXI4; Mouse: Q8VHQ9\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: Acyl-coenzyme A thioesterase 11;Acyl-CoA thioesterase 11;EC 3.1.2.-;Acyl-CoA thioester hydrolase 11;Adipose-associated thioesterase;Brown fat-inducible thioesterase;BFIT\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 26027\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45238960062643,"sku":"BT-AP06003-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45238960095411,"sku":"BT-AP06003-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45238960128179,"sku":"BT-AP06003-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_71b29bb0-e291-446f-b16a-bcd85ebc8ac8.png?v=1769387284","url":"https:\/\/afsbio.com\/products\/aco11-polyclonal-antibody-bt-ap06003","provider":"AFSBio Inc.","version":"1.0","type":"link"}