{"product_id":"actin-alpha-cardiac-muscle-polyclonal-antibody-bt-ap00219","title":"Actin-Alpha cardiac muscle Polyclonal Antibody - BT-AP00219","description":"\u003cp\u003eActin-Alpha cardiac muscle Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP00219-20, BT-AP00219-50, BT-AP00219-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: Actins are highly conserved proteins that are involved in various types of cell motility. Polymerization of globular actin (G-actin) leads to a structural filament (F-actin) in the form of a two-stranded helix. Each actin can bind to four others. Actin alpha cardiac muscle 1 encoded by ACTC1 belongs to the actin family which is comprised of three main groups of actin isoforms, alpha, beta, and gamma. The alpha actins are found in muscle tissues and are a major constituent of the contractile apparatus. Defects in this gene have been associated with idiopathic dilated cardiomyopathy (IDC) and familial hypertrophic cardiomyopathy (FHC).\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Signal Transduction; Cardiovascular\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: ACTC1\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IHC-p, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: Actin-alpha cardiac muscle Antibody\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 42019\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: P68032; Mouse: P68033; Rat: P68035\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: ACTC1; ACTC; Actin, alpha cardiac muscle 1; Alpha-cardiac actin\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 70; Mouse: 11464; Rat: 29275\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45240091672755,"sku":"BT-AP00219-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45240091705523,"sku":"BT-AP00219-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45240091738291,"sku":"BT-AP00219-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_2d359a6d-f4ec-465e-857a-e7f88df2bf9a.png?v=1769403310","url":"https:\/\/afsbio.com\/products\/actin-alpha-cardiac-muscle-polyclonal-antibody-bt-ap00219","provider":"AFSBio Inc.","version":"1.0","type":"link"}