{"product_id":"actinin-α2-monoclonal-antibody-ra10726","title":"Actinin-α2 Monoclonal Antibody - RA10726","description":"\u003cp\u003eActinin-α2 Monoclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSize: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: RA10726-50, RA10726-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: actinin alpha 2 (ACTN2) Homo sapiens Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a muscle-specific, alpha actinin isoform that is expressed in both skeletal and cardiac muscles. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2013],\u003c\/p\u003e\n\n\u003cp\u003eCondition: Purified mouse monoclonal in buffer containing 0.1M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.2% sodium azide, 50% glycerol.\u003c\/p\u003e\n\n\u003cp\u003eStorage Instructions: -20°C\/1 year\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB; IF\/ICC\u003c\/p\u003e\n\n\u003cp\u003eSpecies Cross-Reactivity: Human; Rat; Bovine; Chicken; Dog; Pig; Zebrafish\u003c\/p\u003e\n\n\u003cp\u003eGeneID (Human): 88\u003c\/p\u003e\n\n\u003cp\u003eSWISS: P35609\u003c\/p\u003e\n\n\u003cp\u003eSource: Mouse\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Reed Bio","offers":[{"title":"50μL","offer_id":45118942937267,"sku":"RA10726-50","price":336.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45118942970035,"sku":"RA10726-100","price":448.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_266fa052-eddf-401c-897f-6011b2dee9a2.png?v=1773343573","url":"https:\/\/afsbio.com\/products\/actinin-%ce%b12-monoclonal-antibody-ra10726","provider":"AFSBio Inc.","version":"1.0","type":"link"}