{"product_id":"actinin-alpha3-polyclonal-antibody-bt-ap00218","title":"Actinin-Alpha3 Polyclonal Antibody - BT-AP00218","description":"\u003cp\u003eActinin-Alpha3 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP00218-20, BT-AP00218-50, BT-AP00218-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: ACTN3 encodes a member of the alpha-actin binding protein gene family. Actinin alpha 3 (gene\/pseudogene) is primarily expressed in skeletal muscle and functions as a structural component of sarcomeric Z line. This protein is involved in crosslinking actin containing thin filaments. An allelic polymorphism in this gene results in both coding and non-coding variants; the reference genome represents the coding allele. The non-functional allele of ACTN3 is associated with elite athlete status.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Signal Transduction\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: ACTN3\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IF, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: Actinin-alpha3 Antibody\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 103294\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: Q08043; Mouse: O88990\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: ACTN3; Alpha-actinin-3; Alpha-actinin skeletal muscle isoform 3; F-actin cross-linking protein\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 89; Mouse: 11474\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45240091574451,"sku":"BT-AP00218-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45240091607219,"sku":"BT-AP00218-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45240091639987,"sku":"BT-AP00218-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_312f9ecc-f50b-491e-9405-16b97ad63039.png?v=1769403306","url":"https:\/\/afsbio.com\/products\/actinin-alpha3-polyclonal-antibody-bt-ap00218","provider":"AFSBio Inc.","version":"1.0","type":"link"}