{"product_id":"actr-ic-polyclonal-antibody-bt-ap00224","title":"ACTR-IC Polyclonal Antibody - BT-AP00224","description":"\u003cp\u003eACTR-IC Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP00224-20, BT-AP00224-50, BT-AP00224-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: ACVR1C is a type I receptor for the TGFB (see MIM 190180) family of signaling molecules. Upon ligand binding, type I receptors phosphorylate cytoplasmic SMAD transcription factors, which then translocate to the nucleus and interact directly with DNA or in complex with other transcription factors (Bondestam et al. 2001 [PubMed 12063393]).\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Signal Transduction\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: ACVR1C\u003c\/p\u003e\n\n\u003cp\u003eApplications: IHC-p, IF, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: ACTR-IC Antibody\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 54871\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: Q8NER5; Mouse: Q8K348; Rat: P70539\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: ACVR1C; ALK7; Activin receptor type-1C; Activin receptor type IC; ACTR-IC; Activin receptor-like kinase 7; ALK-7\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 130399; Mouse: 269275; Rat: 245921\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45240092065971,"sku":"BT-AP00224-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45240092098739,"sku":"BT-AP00224-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45240092131507,"sku":"BT-AP00224-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_d712468f-e62f-437b-8bda-d1b89d91db24.png?v=1769403316","url":"https:\/\/afsbio.com\/products\/actr-ic-polyclonal-antibody-bt-ap00224","provider":"AFSBio Inc.","version":"1.0","type":"link"}