{"product_id":"actr-iia-h59-polyclonal-antibody-bs3669","title":"ACTR-IIA (H59) Polyclonal Antibody-BS3669","description":"\u003cp\u003eACTR-IIA (H59) Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BS3669-50, BS3669-100\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50µl, 100µl\u003c\/p\u003e\n\n\u003cp\u003eAlternative Name: Activin receptor type-2A; EC=2.7.11.30; Activin receptor type IIA; ACTR-IIA; ACTRIIA; ACVR2A; ACVR2\u003c\/p\u003e\n\n\u003cp\u003eProduct: Rabbit IgG, 1mg\/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2\u003c\/p\u003e\n\n\u003cp\u003eSwiss-Prot: P27037\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB\u003c\/p\u003e \n\n\u003cp\u003eAll Applications: WB: 1:500~1:1000\u003c\/p\u003e\n\n\u003cp\u003eBackground: Members of the transforming growth factor β superfamily bind to a pair of transmembrane proteins, known as receptor types I and II, which contain serine\/threonine kinases and associate to form a signaling complex. Activin has been shown to bind a heteromeric noncovalent complex, which consists of a type I receptor, ACTR-IA (also designated ACVRI and ALK-2) or ACTR-IB (also designated ALK-4 and SKR2), and a type II receptor, ACTR-IIA (ACVR2A) or ACTR-IIB (ACVR2B). Both receptor types are highly expressed in brain. The activin receptor family members are thought to mediate distinct effects on gene expression, cell differentiation and morphogenesis in a dose dependent manner.\u003c\/p\u003e\n\n\u003cp\u003ePurification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is \u0026gt; 95% (by SDS-PAGE).\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: ACTR-IIA (H59) polyclonal antibody detects endogenous levels of ACTR-IIA protein.\u003c\/p\u003e\n\n\u003cp\u003eBioworld Molecular Weight: ~ 48 kDa\u003c\/p\u003e\n\n\u003cp\u003eNote: For research use only, not for use in diagnostic procedure.\u003c\/p\u003e\n\n\u003cp\u003eExtra Notes: Western blot (WB) analysis of ACTR-IIA (H59) pAb at 1:500 dilution\u003cbr\u003e\nLane 1: AML-12 whole cell lysate(40ug)\u003cbr\u003e\nLane 2: C6 whole cell lysate(40ug)\u003cbr\u003e\nLane 3: HEK293T whole cell lysate(40ug)\u003cbr\u003e\nLane 4: A549 whole cell lysate(40ug)\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Synthetic peptide, corresponding to amino acids 30-80 of Human ACTR-IIA.\u003c\/p\u003e\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eModification: Unmodified\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"50µl","offer_id":42911805866163,"sku":"BS3669-50","price":260.23,"currency_code":"CAD","in_stock":true},{"title":"100µl","offer_id":42911805898931,"sku":"BS3669-100","price":452.94,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_af203b8a-a0f7-4e66-8a0a-8497c0c27d75.jpg?v=1703179608","url":"https:\/\/afsbio.com\/products\/actr-iia-h59-polyclonal-antibody-bs3669","provider":"AFSBio Inc.","version":"1.0","type":"link"}