{"product_id":"acvr2a-polyclonal-antibody-e-ab-15513","title":"ACVR2A Polyclonal Antibody - E-AB-15513","description":"\u003cp\u003eACVR2A Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 60μL, 120μL, 200μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: E-AB-15513-60, E-AB-15513-120, E-AB-15513-200\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: ACVR2A\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: Activin A receptor type IIA; Activin receptor type 2A; Activin receptor type IIA; Activin receptor type-2A; ACTR 2; ACTR IIA; ACTR-IIA; ACTR2; ACTRII; ACTRIIA; Acvr 2; Acvr 2A; Acvr2; ACVR2A; AVR2A; OTTHUMP00000197918\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Cancer, Metabolism, Signal Transduction, Stem Cells\u003c\/p\u003e\n\n\u003cp\u003eConjugation: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eSpecies Reactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eApplication: WB, ELISA\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n \n\n\u003cp\u003eUNIProt ID: P27037\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes activin A type II receptor. Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I (I and IB) and two type II (II and IIB) receptors. These receptors are all transmembrane proteins, composed of a ligand-binding extracellular domain with cysteine-rich region, a transmembrane domain, and a cytoplasmic domain with predicted serine\/threonine specificity. Type I receptors are essential for signaling, and type II receptors are required for binding ligands and for expression of type I receptors. Type I and II receptors form a stable complex after ligand binding, resulting in phosphorylation of type I receptors by type II receptors. Type II receptors are considered to be constitutively active kinases.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1.2 mg\/mL\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Synthetic peptide of human ACVR2A\u003c\/p\u003e\n\n\u003cp\u003eBuffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4\u003c\/p\u003e\n\n\u003cp\u003ePurification Method: Affinity purification\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB 1:500-1:2000\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 58kDa\u003c\/p\u003e\n\n \n\n\u003cp\u003eStorage: -20°C\/One year. Avoid freeze \/ thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: Ice bag\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"60μL","offer_id":43141483954355,"sku":"E-AB-15513-60","price":200.2,"currency_code":"CAD","in_stock":true},{"title":"120μL","offer_id":43141483987123,"sku":"E-AB-15513-120","price":336.0,"currency_code":"CAD","in_stock":true},{"title":"200μL","offer_id":43141484019891,"sku":"E-AB-15513-200","price":558.6,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_b877ce8f-1081-4d63-83bf-5d3eaaf69ba7.png?v=1710156444","url":"https:\/\/afsbio.com\/products\/acvr2a-polyclonal-antibody-e-ab-15513","provider":"AFSBio Inc.","version":"1.0","type":"link"}