{"product_id":"acvr2a-polyclonal-antibody-e-ab-60537","title":"ACVR2A Polyclonal Antibody - E-AB-60537","description":"\u003cp\u003eACVR2A Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 60μL, 120μL, 200μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: E-AB-60537-60, E-AB-60537-120, E-AB-60537-200\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: ACVR2A\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: ACVR2A; ACTRII; ACVR2\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Cancer, Metabolism, Signal Transduction, Stem Cells\u003c\/p\u003e\n\n\u003cp\u003eConjugation: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eSpecies Reactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eApplication: IHC, IF\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n \n\n\u003cp\u003eUNIProt ID: P27037\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes a receptor that mediates the functions of activins, which are members of the transforming growth factor-beta (TGF-beta) superfamily involved in diverse biological processes. The encoded protein is a transmembrane serine-threonine kinase receptor which mediates signaling by forming heterodimeric complexes with various combinations of type I and type II receptors and ligands in a cell-specific manner. The encoded type II receptor is primarily involved in ligand-binding and includes an extracellular ligand-binding domain, a transmembrane domain and a cytoplasmic serine-threonine kinase domain. This gene may be associated with susceptibility to preeclampsia, a pregnancy-related disease which can result in maternal and fetal morbidity and mortality. Alternative splicing results in multiple transcript variants of this gene.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1mg\/mL\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Recombinant fusion protein of human ACVR2A (NP_001607.1).\u003c\/p\u003e\n\n\u003cp\u003eBuffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.\u003c\/p\u003e\n\n\u003cp\u003ePurification Method: Affinity purification\u003c\/p\u003e\n\n\u003cp\u003eDilution: IHC \t1:100-1:200   IF \t1:50-1:200\u003c\/p\u003e\n\n \n\n \n\n\u003cp\u003eStorage: -20°C\/One year. Avoid freeze \/ thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: Ice bag\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"60μL","offer_id":43136822870195,"sku":"E-AB-60537-60","price":280.0,"currency_code":"CAD","in_stock":true},{"title":"120μL","offer_id":43136822902963,"sku":"E-AB-60537-120","price":448.0,"currency_code":"CAD","in_stock":true},{"title":"200μL","offer_id":43136822935731,"sku":"E-AB-60537-200","price":742.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_2a49663a-e37d-4b6c-8880-d0e4bc2c0b3e.png?v=1709992293","url":"https:\/\/afsbio.com\/products\/acvr2a-polyclonal-antibody-e-ab-60537","provider":"AFSBio Inc.","version":"1.0","type":"link"}