{"product_id":"ada11-rabbit-pab-es18463","title":"ADA11 rabbit pAb - ES18463","description":"\u003cp\u003eADA11 rabbit pAb\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: ES18463-50, ES18463-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes a member of the ADAM (a disintegrin and metalloprotease) protein family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The encoded preproprotein is proteolytically processed to generate the mature protease. This gene represents a candidate tumor suppressor gene for human breast cancer based on its location within a minimal region of chromosome 17q21 previously defined by tumor deletion mapping. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. [provided by RefSeq, Jan 2016],\u003c\/p\u003e \n\n\u003cp\u003eAlternate Name: Disintegrin and metalloproteinase domain-containing protein 11 (ADAM 11) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein) (MDC)\u003c\/p\u003e\n\n\u003cp\u003eSource: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB 1:500-2000\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human; Mouse\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Synthesized peptide derived from human ADA11 AA range: 600-650\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: -20°C\/1 year\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eObserved Band (KD): 85kD\u003c\/p\u003e\n\n\u003cp\u003eHuman Gene ID: 4185\u003c\/p\u003e\n\n\u003cp\u003eHuman SWISS Prot NO: O75078\u003c\/p\u003e\n\n\u003cp\u003eSubcellular Location: Membrane; Single-pass type I membrane protein.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ELK Bio","offers":[{"title":"50μL","offer_id":45202424922291,"sku":"ES18463-50","price":207.2,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45202424955059,"sku":"ES18463-100","price":347.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_360x_e4941f14-ac8c-4f98-b7c7-7dc3fd28d3c6.png?v=1767128912","url":"https:\/\/afsbio.com\/products\/ada11-rabbit-pab-es18463","provider":"AFSBio Inc.","version":"1.0","type":"link"}