{"product_id":"adam17-rabbit-monoclonal-antibody-bs40435","title":"ADAM17 Rabbit Monoclonal Antibody-BS40435","description":"\u003cp\u003eADAM17 Rabbit Monoclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50µl, 100µl\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BS40435-50, BS40435-100\u003c\/p\u003e\n\n\u003cp\u003eProduct: Rabbit IgG, 1mg\/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.\u003c\/p\u003e\n\n\u003cp\u003eSwiss-Prot: P78536\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e \n\n\u003cp\u003eApplications: WB, ICC\/IF, IP, , FC\u003c\/p\u003e\n\n\u003cp\u003eAll Applications: WB 1:500~1:2000 ICC\/IF 1:50~1:200 IP 1:50 FC 1:100\u003c\/p\u003e\n\n\u003cp\u003eBackground: TACE is responsible for the shedding of EGFR ligands such as amphiregulin and TNF-α. Some tumors have hyperactivated EGFR due to upregulated TNF-α production and upregulated TACE, making TACE a potential target for drug development. TACE activates Notch in a ligand-independent manner and has been shown to play a role in the development of the Drosophila nervous system.\u003c\/p\u003e\n\n\u003cp\u003ePurification and Purity: Affinity-chromatography\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: ADAM17 Antibody detects endogenous levels of total ADAM17\u003c\/p\u003e\n\n\u003cp\u003eBioworld Molecular Weight: 100kDa\u003c\/p\u003e\n\n\u003cp\u003eNote: For research use only, not for use in diagnostic procedure.\u003c\/p\u003e\n\n\u003cp\u003eExtra Notes: Western blot analysis of ADAM17 expression in Hela cell lysate., Immunofluorescent analysis of Hela cells, using ADAM17 Antibody.\u003c\/p\u003e\n\n\u003cp\u003eAlternative Name: CD156b; ADAM17; CSVP; TACE;\u003c\/p\u003e \n\n\u003cp\u003eImmunogen: A synthesized peptide derived from human ADAM17\u003c\/p\u003e\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eModification: Unmodified\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"50µl","offer_id":42989555876019,"sku":"BS40435-50","price":276.71,"currency_code":"CAD","in_stock":true},{"title":"100µl","offer_id":42989555908787,"sku":"BS40435-100","price":490.83,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_fd3f9b26-abca-4864-b3ea-88cf2647bc2f.jpg?v=1706095331","url":"https:\/\/afsbio.com\/products\/adam17-rabbit-monoclonal-antibody-bs40435","provider":"AFSBio Inc.","version":"1.0","type":"link"}