{"product_id":"adam9-rabbit-polyclonal-antibody-es9357","title":"ADAM9 Rabbit Polyclonal Antibody - ES9357","description":"\u003cp\u003eADAM9 Rabbit Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: ES9357-50, ES9357-100\u003c\/p\u003e\n\n\u003cp\u003eLead times: 1-2 weeks, if manufacturer has product in stock\u003c\/p\u003e\n\n\u003cp\u003eManufacturer\/Ship Location: China\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The protein encoded by this gene interacts with SH3 domain-containing proteins, binds mitotic arrest deficient 2 beta protein, and is also involved in TPA-induced ectodomain shedding of membrane-anchored heparin-binding EGF-like growth factor. Several alternatively spliced transcript variants have been identified for this gene. [provided by RefSeq, Jul 2010],\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Rat, Mouse,\u003c\/p\u003e \n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ELISA\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Synthesized peptide derived from human protein. at AA range: 120-200\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eTarget: ADAM9\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: ADAM9 Polyclonal Antibody detects endogenous levels of protein.\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB 1:500-2000 ELISA 1:5000-20000\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml,\u003c\/p\u003e\n\n\u003cp\u003eFormlation: Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eExpression: Widely expressed, Expressed in chondrocytes, Isoform 2 is highly expressed in liver and heart,\u003c\/p\u003e\n\n\u003cp\u003eObserved Band (KD): 90kD\u003c\/p\u003e\n\n\u003cp\u003eFunction: Caution: Has sometimes been referred to as ADAM-12\u003cbr\u003e\nCofactor: Binds 1 zinc ion per subunit\u003cbr\u003e\nFunction: Probable zinc protease. May mediate cell-cell or cell-matrix interactions. Isoform 2 displays alpha-secretase activity for APP\u003cbr\u003e\nSimilarity: Contains 1 disintegrin domain\u003cbr\u003e\nSimilarity: Contains 1 EGF-like domain\u003cbr\u003e\nSimilarity: Contains 1 peptidase M12B domain\u003cbr\u003e\nTissue Specificity: Widely expressed. Expressed in chondrocytes. Highest expression of isoform 2 found in liver and heart\u003c\/p\u003e\n\n\n\u003cp\u003eSubcellular Location: [Isoform 1]: Cell membrane, Single-pass type I membrane protein, [Isoform 2]: Secreted\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: -20°C\/1 year\u003c\/p\u003e\n\n\u003cp\u003eGene Name: ADAM9 KIAA0021 MCMP MDC9 MLTNG\u003c\/p\u003e\n\n\u003cp\u003eProtein Name: Disintegrin and metalloproteinase domain-containing protein 9 (ADAM 9) (EC 3.4.24.-) (Cellular disintegrin-related protein) (Meltrin-gamma) (Metalloprotease\/disintegrin\/cysteine-rich protein 9) (Myelo\u003c\/p\u003e\n\n\u003cp\u003eMouse SwissProt Number: Q61072\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ELK Biotechnology","offers":[{"title":"50μL","offer_id":46314127229107,"sku":"ES9357-50","price":186.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":46314127261875,"sku":"ES9357-100","price":372.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/elk_antibodies_d75295e2-ffc1-4e0f-a3e7-87715c8983a9.jpg?v=1793190507","url":"https:\/\/afsbio.com\/products\/adam9-rabbit-polyclonal-antibody-es9357","provider":"AFSBio Inc.","version":"1.0","type":"link"}