{"product_id":"adamts17-polyclonal-antibody-bs61126","title":"ADAMTS17 Polyclonal Antibody-BS61126","description":"\u003cp\u003eADAMTS17 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BS61126-50, BS61126-100\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50µl, 100µl\u003c\/p\u003e\n\n\u003cp\u003eProduct: Rabbit IgG, 1mg\/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.\u003c\/p\u003e\n\n\u003cp\u003eSwiss-Prot: Q8TE56\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB\u003c\/p\u003e \n\n\u003cp\u003eAll Applications: WB: 1:500~1:1000\u003c\/p\u003e\n\n\u003cp\u003eBackground: ADAMTS (a disintegrin and metalloproteinase domain with Thrombospondin type-1 modules) is a family of zinc-dependent proteases that are implicated in a variety of normal and pathological conditions, including arthritis and cancer. ADAMTS protein family members contain an N-terminal propeptide domain, a metalloproteinase domain, a disintegrin-like domain and a C-terminus that contains a varying number of Thrombospondin type-1 (TSP-1) motifs. ADAMTS-17 (ADAM metallopeptidase with Thrombospondin type-1 motif, 17) is a 1,095 amino acid secreted protein that belongs to the ADAMTS family. Expressed in liver, prostate, brain and in fetal lung, ADAMTS-17 has seven N-glycosylation sites and shares 56% sequence identity with a related family member, ADAMTS-19. ADAMTS-17 has a conserved cysteine residue in its cysteine-switch motif that, when bound to one zinc ion, inhibits the enzymatic activity of the protein.\u003c\/p\u003e\n\n\u003cp\u003ePurification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is \u0026gt; 95% (by SDS-PAGE).\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: ADAMTS17 polyclonal antibody detects endogenous levels of ADAMTS17 protein.\u003c\/p\u003e\n\n\u003cp\u003eExtra Notes: Western blot (WB) analysis of ADAMTS17 polyclonal antibody at 1:1000 dilution\u003cbr\u003e\nLane1:A549 whole cell lysate(40ug)\u003cbr\u003e\nLane2:HEK293T whole cell lysate(40ug)\u003cbr\u003e\nLane3:U-87MG whole cell lysate(40ug)\u003c\/p\u003e\n\n\u003cp\u003eBioworld Molecular Weight: ~ 121 kDa\u003c\/p\u003e\n\n\u003cp\u003eNote: For research use only, not for use in diagnostic procedure.\u003c\/p\u003e\n\n\u003cp\u003eAlternative Name: A disintegrin and metalloproteinase with thrombospondin motifs 17; ADAM-TS 17; ADAM-TS17; ADAMTS-17; ADAMTS17\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Synthetic peptide, corresponding to Human ADAMTS17.\u003c\/p\u003e\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eModification: Unmodified\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"50µl","offer_id":42910469783731,"sku":"BS61126-50","price":260.23,"currency_code":"CAD","in_stock":true},{"title":"100µl","offer_id":42910469816499,"sku":"BS61126-100","price":452.94,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_57b75641-bc74-4a09-a145-605035b789ce.jpg?v=1703093023","url":"https:\/\/afsbio.com\/products\/adamts17-polyclonal-antibody-bs61126","provider":"AFSBio Inc.","version":"1.0","type":"link"}