{"product_id":"adducinalpha-beta-polyclonal-antibody-bt-ap00260","title":"AdducinAlpha\/Beta Polyclonal Antibody - BT-AP00260","description":"\u003cp\u003eAdducinAlpha\/Beta Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP00260-20, BT-AP00260-50, BT-AP00260-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: Adducins are a family of cytoskeleton proteins encoded by three genes (alpha, beta, gamma). Adducin is a heterodimeric protein that consists of related subunits, which are produced from distinct genes but share a similar structure. Alpha- and beta-adducin include a protease-resistant N-terminal region and a protease-sensitive, hydrophilic C-terminal region. Alpha- and gamma-adducins are ubiquitously expressed. In contrast, beta-adducin is expressed at high levels in brain and hematopoietic tissues. Adducin binds with high affinity to Ca (2+)\/calmodulin and is a substrate for protein kinases A and C. Alternative splicing results in multiple variants encoding distinct isoforms; however, not all variants have been fully described.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Others\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: ADD1\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IHC-p, IP, IF, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: Adducin alpha\/beta Antibody\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 80955\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: P35611\/P35612; Rat: Q63028\/Q05764\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: ADD1; ADDA; Alpha-adducin; Erythrocyte adducin subunit alpha; ADD2; ADDB; Beta-adducin; Erythrocyte adducin subunit beta\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 118\/119; Mouse: 11518\/11519; Rat: 24170\/24171\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45240094130355,"sku":"BT-AP00260-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45240094163123,"sku":"BT-AP00260-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45240094195891,"sku":"BT-AP00260-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_9f3bd887-3ae8-482c-8141-031186d328eb.png?v=1769403343","url":"https:\/\/afsbio.com\/products\/adducinalpha-beta-polyclonal-antibody-bt-ap00260","provider":"AFSBio Inc.","version":"1.0","type":"link"}