{"product_id":"adhx-polyclonal-antibody-bt-ap06085","title":"ADHX Polyclonal Antibody - BT-AP06085","description":"\u003cp\u003eADHX Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP06085-20, BT-AP06085-50, BT-AP06085-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes a member of the alcohol dehydrogenase family. Members of this family metabolize a wide variety of substrates| including ethanol| retinol| other aliphatic alcohols| hydroxysteroids| and lipid peroxidation products. The encoded protein forms a homodimer. It has virtually no activity for ethanol oxidation| but exhibits high activity for oxidation of long-chain primary alcohols and for oxidation of S-hydroxymethyl-glutathione| a spontaneous adduct between formaldehyde and glutathione. This enzyme is an important component of cellular metabolism for the elimination of formaldehyde| a potent irritant and sensitizing agent that causes lacrymation| rhinitis| pharyngitis| and contact dermatitis. The human genome contains several non-transcribed pseudogenes related to this gene.\u003c\/p\u003e \n\n\u003cp\u003eResearch Areas: Signal transduction; Metabolism\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: ADH5\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: Alcohol dehydrogenase class-3\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: P11766; Mouse: P28474; Rat: P12711\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: Alcohol dehydrogenase class-3;EC 1.1.1.1;Alcohol dehydrogenase 5;Alcohol dehydrogenase class chi chain;Alcohol dehydrogenase class-III;Glutathione-dependent formaldehyde dehydrogenase;FALDH\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 128\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45239045685427,"sku":"BT-AP06085-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45239045718195,"sku":"BT-AP06085-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45239045750963,"sku":"BT-AP06085-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_3a1be7ac-f062-486d-a62d-773adf479d60.png?v=1769388338","url":"https:\/\/afsbio.com\/products\/adhx-polyclonal-antibody-bt-ap06085","provider":"AFSBio Inc.","version":"1.0","type":"link"}