{"product_id":"adrb2-polyclonal-antibody-e-ab-92258","title":"ADRB2 Polyclonal Antibody - E-AB-92258","description":"\u003cp\u003eADRB2 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 60μL, 120μL, 200μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: E-AB-92258-60, E-AB-92258-120, E-AB-92258-200\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: ADRB2\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: ADRB2; ADRB2R; ADRBR; B2AR; BAR; BETA2AR\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Cancer, Cardiovascular, Signal Transduction\u003c\/p\u003e\n\n\u003cp\u003eConjugation: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eSpecies Reactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eApplication: WB\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n \n\n\u003cp\u003eUNIProt ID: P07550\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes beta-2-adrenergic receptor which is a member of the G protein-coupled receptor superfamily. This receptor is directly associated with one of its ultimate effectors, the class C L-type calcium channel Ca(V)1.2. This receptor-channel complex also contains a G protein, an adenylyl cyclase, cAMP-dependent kinase, and the counterbalancing phosphatase, PP2A. The assembly of the signaling complex provides a mechanism that ensures specific and rapid signaling by this G protein-coupled receptor. This gene is intronless. Different polymorphic forms, point mutations, and\/or downregulation of this gene are associated with nocturnal asthma, obesity and type 2 diabetes.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1mg\/mL\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: A synthetic peptide of human ADRB2\u003c\/p\u003e\n\n\u003cp\u003eBuffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.\u003c\/p\u003e\n\n\u003cp\u003ePurification Method: Affinity purification\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB 1:500-1:2000\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 46kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 50-100KDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C\/One year. Avoid freeze \/ thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: Ice bag\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"60μL","offer_id":43146631086259,"sku":"E-AB-92258-60","price":280.0,"currency_code":"CAD","in_stock":true},{"title":"120μL","offer_id":43146631119027,"sku":"E-AB-92258-120","price":448.0,"currency_code":"CAD","in_stock":true},{"title":"200μL","offer_id":43146631151795,"sku":"E-AB-92258-200","price":742.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_114e9629-6560-41c4-b3ea-e86ec4d26bc4.png?v=1710298876","url":"https:\/\/afsbio.com\/products\/adrb2-polyclonal-antibody-e-ab-92258","provider":"AFSBio Inc.","version":"1.0","type":"link"}