{"product_id":"af-le-purified-anti-human-cd20-antibody-2h7-e-ab-f12120","title":"AF\/LE Purified Anti-Human CD20 Antibody [2H7] - E-AB-F12120","description":"\u003cp\u003eAF\/LE Purified Anti-Human CD20 Antibody [2H7]\u003c\/p\u003e\n\n\u003cp\u003eSizes: 500μg, 1mg\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: E-AB-F12120-500, E-AB-F12120-1\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: CD20\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: Bp35, Leukocyte surface antigen Leu-16, MS4A1, B-lymphocyte surface antigen B1,\u003c\/p\u003e \n\n\u003cp\u003eConjugation: None (Purified antibody-Azide Free\/Low endotoxin)\u003c\/p\u003e\n\n\u003cp\u003eHost: Mouse\u003c\/p\u003e\n\n\u003cp\u003eSpecies Reactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eApplication: FCM, Depletion\u003c\/p\u003e\n\n\u003cp\u003eUsage: Each lot of this antibody is quality control tested by flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 2.0 µg per 10^6 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.\u003c\/p\u003e\n\n\u003cp\u003eIsotype: Mouse IgG2b, κ\u003c\/p\u003e\n\n\u003cp\u003eClone No.: 2H7\u003c\/p\u003e\n\n\u003cp\u003eUNIProt ID: P11836\u003c\/p\u003e\n\n\u003cp\u003eBackground: CD20 is a 33-37 kD, four transmembrane spanning protein, also known as B1 and Bp35. CD20 is expressed on pre-B-cells, resting and activated B cells (not plasma cells), some follicular dendritic cells, and at low levels on a T cell subset. CD20 is heavily phosphorylated on activated B cells and malignant B cells. Homo-oligomeric complexes of CD20 are thought to form Ca2+ conductive ion channels in the plasma membrane of B cells. The CD20 molecule is involved in B-cell activation and is associated with various Src family kinases (Lyn, Lck, Fyn). It exists in a complex with MHC class I and II, CD53, CD81, and CD82.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 0.5 mg\/mL\u003c\/p\u003e\n\n\u003cp\u003eControl Catalogue Number: E-AB-F098130\u003c\/p\u003e\n\n\u003cp\u003eBuffer: 0.2 μm filtered in PBS, pH 7.2. Azide Free (AF)\/Low Endotoxin (LE): Contains no stabilizers or stabilizers. Endotoxin level is \u0026lt; 2 EU\/mg as Determined by LAL gel clotting assay.\u003c\/p\u003e\n\n\u003cp\u003eGene ID: 931\u003c\/p\u003e\n\n\u003cp\u003eStorage: This product can be stored at 2-8°C for 12 months. Do not freeze.\u003c\/p\u003e\n\n\u003cp\u003eShipping: Ice bag\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"500μg","offer_id":43157188018355,"sku":"E-AB-F12120-500","price":553.0,"currency_code":"CAD","in_stock":true},{"title":"1mg","offer_id":43157188051123,"sku":"E-AB-F12120-1","price":833.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_e1024264-dee9-492f-9901-cced3fd89039.png?v=1710512100","url":"https:\/\/afsbio.com\/products\/af-le-purified-anti-human-cd20-antibody-2h7-e-ab-f12120","provider":"AFSBio Inc.","version":"1.0","type":"link"}