{"product_id":"af-le-purified-anti-human-il-4-antibody-mp4-25d2-e-ab-f12030","title":"AF\/LE Purified Anti-Human IL-4 Antibody [MP4-25D2] - E-AB-F12030","description":"\u003cp\u003eAF\/LE Purified Anti-Human IL-4 Antibody [MP4-25D2]\u003c\/p\u003e\n\n\u003cp\u003eSizes: 500μg, 1mg\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: E-AB-F12030-500, E-AB-F12030-1\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: IL-4\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: Interleukin-4, IL-4, B-cell IgG differentiation factor, B-cell growth factor 1, BSF-1, IGG1 induction factor,\u003c\/p\u003e \n\n\u003cp\u003eConjugation: None (Purified antibody-Azide Free\/Low endotoxin)\u003c\/p\u003e\n\n\u003cp\u003eHost: Rat\u003c\/p\u003e\n\n\u003cp\u003eSpecies Reactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eApplication: ICFCM, Neut\u003c\/p\u003e\n\n\u003cp\u003eUsage: Each lot of this antibody is quality control tested by ELISA assay. Purified MP4-25D2 has been tested by blocking fluorochrome conjugated MP4-25D2 for intracellular cytokine staining. In order to obtain complete blocking results, a saturated amount of purified antibody (≤ 5.0 µg\/million cells) should be used for incubation with target cells, prior to staining with fluorochrome conjugated antibody. It is recommended that the reagent be titrated for optimal performance for each application.\u003c\/p\u003e\n\n\u003cp\u003eIsotype: Rat IgG1, κ\u003c\/p\u003e\n\n\u003cp\u003eClone No.: MP4-25D2\u003c\/p\u003e\n\n\u003cp\u003eUNIProt ID: P05112\u003c\/p\u003e\n\n\u003cp\u003eBackground: IL-4 is a pleiotropic cytokine that is produced by activated T cells, mast cells, and basophils. IL-4 elicits many different biological responses but has two dominant functions. The first is regulating differentiation of naive CD4+ T cell to the Th2 type. Th2 cells produce IL-4, IL-5, IL-10, and IL-13, which tend to favor a humoral immune response while suppressing a cell-mediated immune response controlled by Th1 cells. The second is regulating IgE and IgG1 production by B cells.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 0.5 mg\/mL\u003c\/p\u003e\n\n\u003cp\u003eControl Catalogue Number: E-AB-F098230\u003c\/p\u003e\n\n\u003cp\u003eBuffer: 0.2 μm filtered in PBS, pH 7.2. Azide Free (AF)\/Low Endotoxin (LE): Contains no stabilizers or stabilizers. Endotoxin level is \u0026lt; 2 EU\/mg as Determined by LAL gel clotting assay.\u003c\/p\u003e\n\n\u003cp\u003eGene ID: 3565\u003c\/p\u003e\n\n\u003cp\u003eStorage: This product can be stored at 2-8°C for 12 months. Do not freeze.\u003c\/p\u003e\n\n\u003cp\u003eShipping: Ice bag\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"500μg","offer_id":43157178843315,"sku":"E-AB-F12030-500","price":553.0,"currency_code":"CAD","in_stock":true},{"title":"1mg","offer_id":43157178876083,"sku":"E-AB-F12030-1","price":833.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_d9ea8909-92bf-41de-89d1-0b50b6e13444.png?v=1710512016","url":"https:\/\/afsbio.com\/products\/af-le-purified-anti-human-il-4-antibody-mp4-25d2-e-ab-f12030","provider":"AFSBio Inc.","version":"1.0","type":"link"}