{"product_id":"af-le-purified-anti-mouse-cd120b-tnfr2-antibody-tr75-54-7-e-ab-f10350","title":"AF\/LE Purified Anti-Mouse CD120b\/TNFR2 Antibody [TR75-54.7] - E-AB-F10350","description":"\u003cp\u003eAF\/LE Purified Anti-Mouse CD120b\/TNFR2 Antibody [TR75-54.7]\u003c\/p\u003e\n\n\u003cp\u003eSizes: 500μg, 1mg\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: E-AB-F10350-500, E-AB-F10350-1\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: CD120b\/TNFR2\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: Tumor necrosis factor receptor superfamily member 1B, Tnfrsf1b, Tumor necrosis factor receptor 2, TNF-R2, TNF-RII, TNFR-II, p75, p80 TNF-alpha receptor, CD120b,\u003c\/p\u003e \n\n\u003cp\u003eConjugation: None (Purified antibody-Azide Free\/Low endotoxin)\u003c\/p\u003e\n\n\u003cp\u003eHost: Armenian Hamster\u003c\/p\u003e\n\n\u003cp\u003eSpecies Reactivity: Mouse\u003c\/p\u003e\n\n\u003cp\u003eApplication: FCM,Block\u003c\/p\u003e\n\n\u003cp\u003eUsage: Each lot of this antibody is quality control tested by flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.25 µg per 10^6 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.\u003c\/p\u003e\n\n\u003cp\u003eIsotype: Armenian Hamster IgG\u003c\/p\u003e\n\n\u003cp\u003eClone No.: TR75-54.7\u003c\/p\u003e\n\n\u003cp\u003eUNIProt ID: P25119\u003c\/p\u003e\n\n\u003cp\u003eBackground: CD120b is a 75 kD type I transmembrane protein, also known as Tumor Necrosis Factor Receptor Type II (TNFRII) or p75. It is expressed on a variety of cells at low levels, the expression is upregulated upon activation. This receptor binds both TNF-α and LT-α (also known as TNF-β). In association with TRAF1 and TRAF2, the receptor crosslinking induced by TNF-α or LT-α trimers is critical for signal transduction, leading to apoptosis, NF-kB activation, increased expression of proinflammatory genes, tumor necrosis, and cell differentiation depending on cell type and differentiation state.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 0.5 mg\/mL\u003c\/p\u003e\n\n\u003cp\u003eControl Catalogue Number: E-AB-F098530\u003c\/p\u003e\n\n\u003cp\u003eBuffer: 0.2 μm filtered in PBS, pH 7.2. Azide Free (AF)\/Low Endotoxin (LE): Contains no stabilizers or stabilizers. Endotoxin level is \u0026lt; 2 EU\/mg as Determined by LAL gel clotting assay.\u003c\/p\u003e\n\n\u003cp\u003eGene ID: 21938\u003c\/p\u003e\n\n\u003cp\u003eStorage: This product can be stored at 2-8°C for 12 months. Do not freeze.\u003c\/p\u003e\n\n\u003cp\u003eShipping: Ice bag\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"500μg","offer_id":43157087289523,"sku":"E-AB-F10350-500","price":553.0,"currency_code":"CAD","in_stock":true},{"title":"1mg","offer_id":43157087322291,"sku":"E-AB-F10350-1","price":833.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_c0652242-e963-42d4-92d2-4f0ae5ed02a1.png?v=1710510679","url":"https:\/\/afsbio.com\/products\/af-le-purified-anti-mouse-cd120b-tnfr2-antibody-tr75-54-7-e-ab-f10350","provider":"AFSBio Inc.","version":"1.0","type":"link"}