{"product_id":"af-le-purified-anti-mouse-cd209b-antibody-22d1-e-ab-f10220","title":"AF\/LE Purified Anti-Mouse CD209b Antibody [22D1] - E-AB-F10220","description":"\u003cp\u003eAF\/LE Purified Anti-Mouse CD209b Antibody [22D1]\u003c\/p\u003e\n\n\u003cp\u003eSizes: 500μg, 1mg\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: E-AB-F10220-500, E-AB-F10220-1\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: CD209b\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: CD209 antigen-like protein B, Cd209b, DC-SIGN-related protein 1, DC-SIGNR1, OtB7, CD209, Cd209b,\u003c\/p\u003e \n\n\u003cp\u003eConjugation: None (Purified antibody-Azide Free\/Low endotoxin)\u003c\/p\u003e\n\n\u003cp\u003eHost: Armenian Hamster\u003c\/p\u003e\n\n\u003cp\u003eSpecies Reactivity: Mouse\u003c\/p\u003e\n\n\u003cp\u003eApplication: FCM\u003c\/p\u003e\n\n\u003cp\u003eUsage: Each lot of this antibody is quality control tested by flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.5 µg per 10^6 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.\u003c\/p\u003e\n\n\u003cp\u003eIsotype: Armenian Hamster IgG\u003c\/p\u003e\n\n\u003cp\u003eClone No.: 22D1\u003c\/p\u003e\n\n\u003cp\u003eUNIProt ID: Q8CJ91\u003c\/p\u003e\n\n\u003cp\u003eBackground: CD209B, also known as SIGN-R1, is a mouse C-type lectin receptor predominantly expressed on macrophages in the spleen marginal zone and lymph nodes medulla. CD209B is a mouse homolog of human CD209\/DC-SIGN and is involved in innate immune response. CD209B mediates the recognition and uptake of pathogen products, such as lipopolysaccharides (LPS), pneumococcal polysaccharides, and dextrans. CD209B has been demonstrated to facilitate the clearance of encapsulated pneumococcus by directly binding to C1q and activating complement through an immunoglobulin independent pathway.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 0.5 mg\/mL\u003c\/p\u003e\n\n\u003cp\u003eControl Catalogue Number: E-AB-F098530\u003c\/p\u003e\n\n\u003cp\u003eBuffer: 0.2 μm filtered in PBS, pH 7.2. Azide Free (AF)\/Low Endotoxin (LE): Contains no stabilizers or stabilizers. Endotoxin level is \u0026lt; 2 EU\/mg as Determined by LAL gel clotting assay.\u003c\/p\u003e\n\n\u003cp\u003eGene ID: 69165\u003c\/p\u003e\n\n\u003cp\u003eStorage: This product can be stored at 2-8°C for 12 months. Do not freeze.\u003c\/p\u003e\n\n\u003cp\u003eShipping: Ice bag\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"500μg","offer_id":43157080539315,"sku":"E-AB-F10220-500","price":553.0,"currency_code":"CAD","in_stock":true},{"title":"1mg","offer_id":43157080572083,"sku":"E-AB-F10220-1","price":833.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_c9ebb0b9-4780-47aa-978d-0b275ae3ff65.png?v=1710510525","url":"https:\/\/afsbio.com\/products\/af-le-purified-anti-mouse-cd209b-antibody-22d1-e-ab-f10220","provider":"AFSBio Inc.","version":"1.0","type":"link"}