{"product_id":"af-le-purified-anti-mouse-tcr-γ-δ-antibody-uc7-13d5-e-ab-f11240","title":"AF\/LE Purified Anti-Mouse TCR γ\/δ Antibody [UC7-13D5] - E-AB-F11240","description":"\u003cp\u003eAF\/LE Purified Anti-Mouse TCR γ\/δ Antibody [UC7-13D5]\u003c\/p\u003e\n\n\u003cp\u003eSizes: 500μg, 1mg\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: E-AB-F11240-500, E-AB-F11240-1\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: TCR γ\/δ\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: TCR-γ\/δ, γ\/δ TCR,\u003c\/p\u003e \n\n\u003cp\u003eConjugation: None (Purified antibody-Azide Free\/Low endotoxin)\u003c\/p\u003e\n\n\u003cp\u003eHost: Armenian Hamster\u003c\/p\u003e\n\n\u003cp\u003eSpecies Reactivity: Mouse\u003c\/p\u003e\n\n\u003cp\u003eApplication: FCM\u003c\/p\u003e\n\n\u003cp\u003eUsage: Each lot of this antibody is quality control tested by flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per 10^6 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.\u003c\/p\u003e\n\n\u003cp\u003eIsotype: Armenian Hamster IgG\u003c\/p\u003e\n\n\u003cp\u003eClone No.: UC7-13D5\u003c\/p\u003e\n\n\u003cp\u003eBackground: T cell receptor (TCR) is a heterodimer consisting of an α and a β chain (TCR α\/β) or a γ and a δ chain (TCR γ\/δ). TCR γ\/δ belongs to the immunoglobulin superfamily, involved in the recognition of certain bacterial and tumor antigens bound to MHC class I. The TCR γ\/δ associates with CD3 and is expressed on a T cell subset found in the thymus, the intestinal epithelium, and the peripheral lymphoid tissues and peritoneum. Most γ\/δ T cells are CD4-\/CD8-, some are CD8+. T cells expressing the TCR γ\/δ have been shown to play a role in oral tolerance, tumor-associated tolerance, and autoimmune disease. It has been reported that γ\/δ T cells also play a principal role in antigen presentation. Immobilized UC7-13D5 antibody has been reported to activate TCR-γ\/δ-bearing T cells in vitro, and to deplete peripheral TCR-γ\/δ-bearing T cells in vivo.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 0.5 mg\/mL\u003c\/p\u003e\n\n\u003cp\u003eControl Catalogue Number: E-AB-F098530\u003c\/p\u003e\n\n\u003cp\u003eBuffer: 0.2 μm filtered in PBS, pH 7.2. Azide Free (AF)\/Low Endotoxin (LE): Contains no stabilizers or stabilizers. Endotoxin level is \u0026lt; 2 EU\/mg as Determined by LAL gel clotting assay.\u003c\/p\u003e\n\n\u003cp\u003eGene ID: 110066110067\u003c\/p\u003e\n\n\u003cp\u003eStorage: This product can be stored at 2-8°C for 12 months. Do not freeze.\u003c\/p\u003e\n\n\u003cp\u003eShipping: Ice bag\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"500μg","offer_id":43157069037747,"sku":"E-AB-F11240-500","price":343.0,"currency_code":"CAD","in_stock":true},{"title":"1mg","offer_id":43157069070515,"sku":"E-AB-F11240-1","price":623.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_4d5c086e-e290-4aa9-9579-9d828addf8ad.png?v=1710510282","url":"https:\/\/afsbio.com\/products\/af-le-purified-anti-mouse-tcr-%ce%b3-%ce%b4-antibody-uc7-13d5-e-ab-f11240","provider":"AFSBio Inc.","version":"1.0","type":"link"}