{"product_id":"afp-monoclonal-antibody-bt-mca2176","title":"AFP Monoclonal Antibody - BT-MCA2176","description":"\u003cp\u003eAFP Monoclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Number: BT-MCA2176-50, BT-MCA2176-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: AFP (alpha-fetoprotein), a major plasma protein produced by the yolk sac and the liver during fetal life. Alpha-fetoprotein expression in adults is often associated with hepatoma or teratoma. However, hereditary persistance of alpha-fetoprotein may also be found in individuals with no obvious pathology. The protein is thought to be the fetal counterpart of serum albumin, and the alpha-fetoprotein and albumin genes are present in tandem in the same transcriptional orientation on chromosome 4. Alpha-fetoprotein is found in monomeric as well as dimeric and trimeric forms, and binds copper, nickel, fatty acids and bilirubin. The level of alpha-fetoprotein in amniotic fluid is used to measure renal loss of protein to screen for spina bifida and anencephaly.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Cardiovascular, Cancer\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: AFP\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eClonality: Monoclonal\u003c\/p\u003e\n\n\u003cp\u003eClone ID: 6E6\u003c\/p\u003e\n\n\u003cp\u003eHost: Mouse\u003c\/p\u003e\n\n\u003cp\u003eIsotype: Mouse IgG2b\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: AFP\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Purified recombinant fragment of human AFP expressed in E. Coli.\u003c\/p\u003e\n\n\u003cp\u003eStorage: 4°C|-20°C for long term storage\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Ascitic fluid containing 0.03% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 69kDa\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: P02771\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: alpha-fetoprotein, FETA, HPAFP\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 174\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"50μL","offer_id":45238630908083,"sku":"BT-MCA2176-50","price":308.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45238630940851,"sku":"BT-MCA2176-100","price":448.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_21f4e340-de9f-4d3d-bdc9-13d9a23c2f0c.png?v=1769383233","url":"https:\/\/afsbio.com\/products\/afp-monoclonal-antibody-bt-mca2176","provider":"AFSBio Inc.","version":"1.0","type":"link"}