{"product_id":"afp-monoclonal-antibody-bt-mca4562","title":"AFP Monoclonal Antibody - BT-MCA4562","description":"\u003cp\u003eAFP Monoclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Number: BT-MCA4562-50, BT-MCA4562-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes alpha-fetoprotein, a major plasma protein produced by the yolk sac and the liver during fetal life. Alpha-fetoprotein expression in adults is often associated with hepatocarcinoma and with teratoma, and has prognostic value for managing advanced gastric cancer. However, hereditary persistance of alpha-fetoprotein may also be found in individuals with no obvious pathology. The protein is thought to be the fetal counterpart of serum albumin, and the alpha-fetoprotein and albumin genes are present in tandem in the same transcriptional orientation on chromosome 4. Alpha-fetoprotein is found in monomeric as well as dimeric and trimeric forms, and binds copper, nickel, fatty acids and bilirubin. The level of alpha-fetoprotein in amniotic fluid is used to measure renal loss of protein to screen for spina bifida and anencephaly.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Cardiovascular, Cancer\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: AFP\u003c\/p\u003e\n\n\u003cp\u003eApplications: IHC, FCM\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eClonality: Monoclonal\u003c\/p\u003e\n\n\u003cp\u003eClone ID: 2G4H3\u003c\/p\u003e\n\n\u003cp\u003eHost: Mouse\u003c\/p\u003e\n\n\u003cp\u003eIsotype: Mouse IgG2b\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: AFP\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Purified recombinant fragment of human AFP (AA: 19-210) expressed in HEK293-6e cells supernatant.\u003c\/p\u003e\n\n\u003cp\u003eStorage: 4°C|-20°C for long term storage\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Purified antibody in PBS with 0.05% sodium azide\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 68.6kDa\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: P02771\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: AFPD, FETA, HPAFP\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 174\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"50μL","offer_id":45238503866547,"sku":"BT-MCA4562-50","price":308.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45238503899315,"sku":"BT-MCA4562-100","price":448.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_8577cc93-ee97-4770-8839-7bbf45cfaada.png?v=1769381907","url":"https:\/\/afsbio.com\/products\/afp-monoclonal-antibody-bt-mca4562","provider":"AFSBio Inc.","version":"1.0","type":"link"}