{"product_id":"agr2-polyclonal-antibody-bs90038","title":"AGR2 Polyclonal Antibody-BS90038","description":"\u003cp\u003eAGR2 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50µl, 100µl\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BS90038-50, BS90038-100\u003c\/p\u003e\n\n\u003cp\u003eProduct: Rabbit IgG, 1mg\/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2\u003c\/p\u003e\n\n\u003cp\u003eSwiss-Prot: O95994(Human)\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ICC, IHC, IP,  FC\u003c\/p\u003e\n\n\u003cp\u003eAll Applications: WB:1:1,000-1:5,000\u003cbr\u003e\nICC:1:100-1:500\u003cbr\u003e\nIHC:1:50-1:200\u003cbr\u003e\nFC:1:50-1:100\u003c\/p\u003e\n\n\u003cp\u003eBackground: AGR2 (Anterior Gradient Protein 2), also known as AG2, GOB-4 or HAG-2, is a member of the anterior gradient homolog family. It is the human ortholog of XAG-2, the secreted Xenopus laevis Anterior Gradient protein. In X. laevis, it is involved in cement gland differentiation and neural marker gene expression. AGR2 is a secretory protein encoded by two different AGR2 transcripts. It interacts with LYPD3 and α-dystroglycan (DAG-1). AGR2 is ubiquitously expressed with up-regulated expression in prostate cancer, breast cancer, lung cancer, renal carcinomas and endometrial carcinomas. AGR2 expression is positively correlated with that of the estrogen receptor (ER) and is negatively correlated with that of the epidermal growth factor receptor (EGFR). AGR2 may serve as a potential therapeutic marker for various cancers.\u003c\/p\u003e\n\n\u003cp\u003ePurification and Purity: ProA affinity purified\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze \/ thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: AGR2 polyclonal antibody detects endogenous levels of AGR2 protein.\u003c\/p\u003e\n\n\u003cp\u003eBioworld Molecular Weight: 17 kDa\u003c\/p\u003e\n\n\u003cp\u003eNote: For research use only, not for use in diagnostic procedure.\u003c\/p\u003e\n\n\u003cp\u003eExtra Notes: Western blot analysis of AGR2 on MCF-7 cells lysates using anti-AGR2 antibody at 1\/1,000 dilution., ICC staining AGR2 in Hela cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100\/PBS.\u003c\/p\u003e\n\n\u003cp\u003eAlternative Name: AG-2, hAG-2, AGR2, AG 2, AG 2 protein, AG-2, AG2, AG2 protein, AGR 2, AGR2, AGR2, Anterior gradient 2 homolog (Xenopus laevis), anterior gradient 2 homolog, Anterior gradient 2, Xenopus, homolog of, Anterior gradient homolog 2, Anterior gradient protein 2 homolog, GOB 4, GOB4, HAG 2, hAG-2, hAG2, HAG2\/R, HPC 8, hPC8, PDIA17, Protein disulfide isomerase family A member 17, secreted cement gland homolog, Secreted cement gland protein XAG 2 homolog, Secreted cement gland protein XAG-2 homolog, Secreted cement gland protein XAG2 homolog, XAG 2, XAG2,\u003c\/p\u003e \n\n\u003cp\u003eImmunogen: recombinant protein\u003c\/p\u003e\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eModification: Unmodified\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"50µl","offer_id":42979758440627,"sku":"BS90038-50","price":424.94,"currency_code":"CAD","in_stock":true},{"title":"100µl","offer_id":42979758473395,"sku":"BS90038-100","price":655.54,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_73e9777d-920b-4b61-b828-5d1b208152bf.jpg?v=1705748711","url":"https:\/\/afsbio.com\/products\/agr2-polyclonal-antibody-bs90038","provider":"AFSBio Inc.","version":"1.0","type":"link"}