{"product_id":"aid-rabbit-pab-es4296","title":"AID rabbit pAb - ES4296","description":"\u003cp\u003eAID rabbit pAb\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: ES4296-50, ES4296-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes a RNA-editing deaminase that is a member of the cytidine deaminase family. The protein is involved in somatic hypermutation, gene conversion, and class-switch recombination of immunoglobulin genes. Defects in this gene are the cause of autosomal recessive hyper-IgM immunodeficiency syndrome type 2 (HIGM2). [provided by RefSeq, Feb 2009],\u003c\/p\u003e \n\n\u003cp\u003eAlternate Name: AICDA; AID; Activation-induced cytidine deaminase; Cytidine aminohydrolase\u003c\/p\u003e\n\n\u003cp\u003eSource: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB; IHC; IF; ELISA\u003c\/p\u003e\n\n\u003cp\u003eDilution: Western Blot: 1\/500 - 1\/2000. IHC-p: 1:100-1:300. ELISA: 1\/10000. Not yet tested in other applications.\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human; Mouse; Rat\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from the Internal region of human AICDA. AA range:81-130\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: -20°C\/1 year\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eObserved Band (KD): 24kD\u003c\/p\u003e\n\n\u003cp\u003eHuman Gene ID: 57379\u003c\/p\u003e\n\n\u003cp\u003eHuman SWISS Prot NO: Q9GZX7\u003c\/p\u003e\n\n\u003cp\u003eSubcellular Location: Nucleus. Cytoplasm. Predominantly cytoplasmic (PubMed:21385873). In the presence of MCM3AP\/GANP, relocalizes to the nucleus (By similarity).\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ELK Bio","offers":[{"title":"50μL","offer_id":45202189025459,"sku":"ES4296-50","price":207.2,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45202189058227,"sku":"ES4296-100","price":347.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_360x_f1e15be6-8557-45e3-a655-6bfce44478f6.png?v=1767123855","url":"https:\/\/afsbio.com\/products\/aid-rabbit-pab-es4296","provider":"AFSBio Inc.","version":"1.0","type":"link"}