{"product_id":"ak1c4-polyclonal-antibody-bt-ap06132","title":"AK1C4 Polyclonal Antibody - BT-AP06132","description":"\u003cp\u003eAK1C4 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP06132-20, BT-AP06132-50, BT-AP06132-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes a member of the aldo\/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and\/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the bioreduction of chlordecone, a toxic organochlorine pesticide, to chlordecone alcohol in liver. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14.\u003c\/p\u003e \n\n\u003cp\u003eResearch Areas: Cancer; Metabolism; Signal transduction\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: AKR1C4\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Rat, Mouse\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: Aldo-keto reductase family 1 member C4\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: P17516\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: Aldo-keto reductase family 1 member C4;EC 1.1.1.-;3-alpha-HSD1;3-alpha-hydroxysteroid dehydrogenase type I;EC 1.1.1.50;Chlordecone reductase;CDR;EC 1.1.1.225;Dihydrodiol dehydrogenase 4\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 1109\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45239047717043,"sku":"BT-AP06132-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45239047749811,"sku":"BT-AP06132-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45239047782579,"sku":"BT-AP06132-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_364bed6c-2044-4cb1-a3ee-9d1a21ba5c07.png?v=1769388378","url":"https:\/\/afsbio.com\/products\/ak1c4-polyclonal-antibody-bt-ap06132","provider":"AFSBio Inc.","version":"1.0","type":"link"}