{"product_id":"akap12-polyclonal-antibody-e-ab-12884","title":"AKAP12 Polyclonal Antibody - E-AB-12884","description":"\u003cp\u003eAKAP12 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 60μL, 120μL, 200μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: E-AB-12884-60, E-AB-12884-120, E-AB-12884-200\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: AKAP12\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: A kinase (PRKA) anchor protein (gravin) 12; A kinase Anchor Protein 12; A kinase anchor protein 250kDa; A-kinase anchor protein 12; A-kinase anchor protein 250 kDa; AKA12; AKAP 12; AKAP 250; AKAP-12; Akap12; AKAP250; DKFZp686M0430; DKFZp686O0331; FLJ20945; FLJ97621; Gercelin; Gravin; Kinase scaffold protein gravin; Myasthenia gravis autoantigen; Myasthenia gravis autoantigen gravin; OTTHUMP00000017426; OTTHUMP00000017427; Src-Suppressed C Kinase Substrate; Srcs5; SSeCKS; Tsga12\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Cancer, Neuroscience, Signal Transduction\u003c\/p\u003e\n\n\u003cp\u003eConjugation: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eSpecies Reactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eApplication: IHC, ELISA\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eUNIProt ID: Q02952\u003c\/p\u003e\n\n\u003cp\u003eBackground: The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. The encoded protein is expressed in endothelial cells, cultured fibroblasts, and osteosarcoma cells. It associates with protein kinases A and C and phosphatase, and serves as a scaffold protein in signal transduction. This protein and RII PKA colocalize at the cell periphery. This protein is a cell growth-related protein. Antibodies to this protein can be produced by patients with myasthenia gravis. Alternative splicing of this gene results in two transcript variants encoding different isoforms.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 0.4 mg\/mL\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Synthetic peptide of human AKAP12\u003c\/p\u003e\n\n\u003cp\u003eBuffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4\u003c\/p\u003e\n\n\u003cp\u003ePurification Method: Affinity purification\u003c\/p\u003e\n\n\u003cp\u003eDilution: IHC 1:50-1:200\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C\/One year. Avoid freeze \/ thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: Ice bag\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"200μL","offer_id":43124104364211,"sku":"E-AB-12884-200","price":558.6,"currency_code":"CAD","in_stock":true},{"title":"120μL","offer_id":43124104396979,"sku":"E-AB-12884-120","price":336.0,"currency_code":"CAD","in_stock":true},{"title":"60μL","offer_id":43124104429747,"sku":"E-AB-12884-60","price":200.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_01dd2236-4ecd-426c-b264-c748ecc2067e.png?v=1709723996","url":"https:\/\/afsbio.com\/products\/akap12-polyclonal-antibody-e-ab-12884","provider":"AFSBio Inc.","version":"1.0","type":"link"}