{"product_id":"akr1c1-polyclonal-antibody-e-ab-64412","title":"AKR1C1 Polyclonal Antibody - E-AB-64412","description":"\u003cp\u003eAKR1C1 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 60μL, 120μL, 200μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: E-AB-64412-60, E-AB-64412-120, E-AB-64412-200\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: AKR1C1\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: AKR1C1; 2-ALPHA-HSD; 20-ALPHA-HSD; C9; DD1; DD1\/DD2; DDH; DDH1; H-37; HAKRC; HBAB; MBAB\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Metabolism, Developmental Biology, Signal Transduction\u003c\/p\u003e\n\n\u003cp\u003eConjugation: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eSpecies Reactivity: Human, Mouse\u003c\/p\u003e\n\n\u003cp\u003eApplication: WB\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n \n\n\u003cp\u003eUNIProt ID: Q04828\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes a member of the aldo\/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and\/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the reaction of progesterone to the inactive form 20-alpha-hydroxy-progesterone. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1mg\/mL\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Recombinant fusion protein of human AKR1C1 (NP_001344.2).\u003c\/p\u003e\n\n\u003cp\u003eBuffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.\u003c\/p\u003e\n\n\u003cp\u003ePurification Method: Affinity purification\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB \t1:1000-1:3000\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 36kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 38kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C\/One year. Avoid freeze \/ thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: Ice bag\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"60μL","offer_id":43146325000371,"sku":"E-AB-64412-60","price":280.0,"currency_code":"CAD","in_stock":true},{"title":"120μL","offer_id":43146325033139,"sku":"E-AB-64412-120","price":448.0,"currency_code":"CAD","in_stock":true},{"title":"200μL","offer_id":43146325065907,"sku":"E-AB-64412-200","price":742.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_559f3dc3-3024-48dd-977a-e2c3a0550fac.png?v=1710293686","url":"https:\/\/afsbio.com\/products\/akr1c1-polyclonal-antibody-e-ab-64412","provider":"AFSBio Inc.","version":"1.0","type":"link"}