{"product_id":"akr1c2-polyclonal-antibody-e-ab-65772","title":"AKR1C2 Polyclonal Antibody - E-AB-65772","description":"\u003cp\u003eAKR1C2 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 60μL, 120μL, 200μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: E-AB-65772-60, E-AB-65772-120, E-AB-65772-200\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: AKR1C2\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: AKR1C2; AKR1C-pseudo; BABP; DD; DD-2; DD\/BABP; DD2; DDH2; HAKRD; HBAB; MCDR2; SRXY8; TDD\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Cancer, Metabolism, Signal Transduction\u003c\/p\u003e\n\n\u003cp\u003eConjugation: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eSpecies Reactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eApplication: WB, IF\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n \n\n\u003cp\u003eUNIProt ID: P52895\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes a member of the aldo\/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols using NADH and\/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme binds bile acid with high affinity, and shows minimal 3-alpha-hydroxysteroid dehydrogenase activity. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14. Three transcript variants encoding two different isoforms have been found for this gene.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1mg\/mL\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Recombinant fusion protein of human AKR1C2 (NP_995317.1).\u003c\/p\u003e\n\n\u003cp\u003eBuffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.\u003c\/p\u003e\n\n\u003cp\u003ePurification Method: Affinity purification\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB \t1:500-1:2000   IF \t1:50-1:100\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 15kDa\/36kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 37kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C\/One year. Avoid freeze \/ thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: Ice bag\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"60μL","offer_id":43146387947699,"sku":"E-AB-65772-60","price":280.0,"currency_code":"CAD","in_stock":true},{"title":"120μL","offer_id":43146387980467,"sku":"E-AB-65772-120","price":448.0,"currency_code":"CAD","in_stock":true},{"title":"200μL","offer_id":43146388013235,"sku":"E-AB-65772-200","price":742.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_a28d1dd7-e534-49b1-b2cf-e2966e9c4b52.png?v=1710294679","url":"https:\/\/afsbio.com\/products\/akr1c2-polyclonal-antibody-e-ab-65772","provider":"AFSBio Inc.","version":"1.0","type":"link"}