{"product_id":"akr7a2-polyclonal-antibody-e-ab-60266","title":"AKR7A2 Polyclonal Antibody - E-AB-60266","description":"\u003cp\u003eAKR7A2 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 60μL, 120μL, 200μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: E-AB-60266-60, E-AB-60266-120, E-AB-60266-200\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: AKR7A2\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: AKR7A2; AFAR; AFAR1; AFB1-AR1; AKR7\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Metabolism,Neuroscience,Signal Transduction\u003c\/p\u003e\n\n\u003cp\u003eConjugation: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eSpecies Reactivity: Human, Mouse\u003c\/p\u003e\n\n\u003cp\u003eApplication: WB\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n \n\n\u003cp\u003eUNIProt ID: O43488\u003c\/p\u003e\n\n\u003cp\u003eBackground: The protein encoded by this gene belongs to the aldo\/keto reductase (AKR) superfamily and AKR7 family, which are involved in the detoxification of aldehydes and ketones. The AKR7 family consists of 3 genes that are present in a cluster on the p arm of chromosome 1. This protein, thought to be localized in the golgi, catalyzes the NADPH-dependent reduction of succinic semialdehyde to the endogenous neuromodulator, gamma-hydroxybutyrate. It may also function as a detoxication enzyme in the reduction of aflatoxin B1 and 2-carboxybenzaldehyde. Alternative splicing results in multiple transcript variants.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/mL\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Recombinant fusion protein of human AKR7A2\u003c\/p\u003e\n\n\u003cp\u003eBuffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.\u003c\/p\u003e\n\n\u003cp\u003ePurification Method: Affinity purification\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB 1:500-1:2000\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 39kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 35kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C\/One year. Avoid freeze \/ thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: Ice bag\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"60μL","offer_id":43146046668979,"sku":"E-AB-60266-60","price":280.0,"currency_code":"CAD","in_stock":true},{"title":"120μL","offer_id":43146046701747,"sku":"E-AB-60266-120","price":448.0,"currency_code":"CAD","in_stock":true},{"title":"200μL","offer_id":43146046734515,"sku":"E-AB-60266-200","price":742.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_0f42eec2-e5c7-4bf2-bc92-502f5324377c.png?v=1710290550","url":"https:\/\/afsbio.com\/products\/akr7a2-polyclonal-antibody-e-ab-60266","provider":"AFSBio Inc.","version":"1.0","type":"link"}