{"product_id":"akt-panrabbit-monoclonal-antibody-ra12276","title":"Akt (pan)Rabbit Monoclonal Antibody - RA12276","description":"\u003cp\u003eAkt (pan)Rabbit Monoclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: RA12276-50, RA12276-100\u003c\/p\u003e\n\n\u003cp\u003eLead times: 1-2 weeks, if manufacturer has product in stock\u003c\/p\u003e\n\n\u003cp\u003eManufacturer\/Ship Location: China\u003c\/p\u003e\n\n\u003cp\u003eBackground: AKT1 gene encodes one of the three members of the human AKT serine-threonine protein kinase family which are often referred to as protein kinase B alpha, beta, and gamma. These highly similar AKT proteins all have an N-terminal pleckstrin homology domain, a serine\/threonine-specific kinase domain and a C-terminal regulatory domain. These proteins are phosphorylated by phosphoinositide 3-kinase (PI3K). AKT\/PI3K forms a key component of many signalling pathways that involve the binding of membrane-bound ligands such as receptor tyrosine kinases, G-protein coupled receptors, and integrin-linked kinase. These AKT proteins therefore regulate a wide variety of cellular functions including cell proliferation, survival, metabolism, and angiogenesis in both normal and malignant cells.\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IHC, IF, ELISA\u003c\/p\u003e\n\n\u003cp\u003eAlternate Names: AKT1\/AKT2\/AKT3\u003c\/p\u003e\n\n\u003cp\u003eClonality: Monoclonal\u003c\/p\u003e\n\n\u003cp\u003eDilution: IHC 1:200-1:1000; WB 1:2000-1:10000; IF 1:200-1:1000; ELISA 1:5000-1:20000; IP 1:50-1:200;Note:For IHC, wesuggest antigen retrieval with TE buffer pH 9.0\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C\/1 year\u003c\/p\u003e\n\n\u003cp\u003eCondition: Liquid in PBS, 50% glycerol, 0.05% Proclin 300, 0.05% BSA\u003c\/p\u003e\n\n\u003cp\u003eHuman Gene ID: 207;208;10000\u003c\/p\u003e\n\n\u003cp\u003eProtein Molecular Weight（KDa): 55\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight: 55\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Reed Biotech","offers":[{"title":"50μL","offer_id":45901067223219,"sku":"RA12276-50","price":360.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45901067255987,"sku":"RA12276-100","price":480.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/Reed_Product_image.png?v=1787771796","url":"https:\/\/afsbio.com\/products\/akt-panrabbit-monoclonal-antibody-ra12276","provider":"AFSBio Inc.","version":"1.0","type":"link"}