{"product_id":"al1l1-rabbit-polyclonal-antibody-es18410","title":"AL1L1 Rabbit Polyclonal Antibody - ES18410","description":"\u003cp\u003eAL1L1 Rabbit Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: ES18410-50, ES18410-100\u003c\/p\u003e\n\n\u003cp\u003eLead times: 1-2 weeks, if manufacturer has product in stock\u003c\/p\u003e\n\n\u003cp\u003eManufacturer\/Ship Location: China\u003c\/p\u003e\n\n\u003cp\u003eBackground: The protein encoded by this gene catalyzes the conversion of 10-formyltetrahydrofolate, nicotinamide adenine dinucleotide phosphate (NADP+), and water to tetrahydrofolate, NADPH, and carbon dioxide. The encoded protein belongs to the aldehyde dehydrogenase family. Loss of function or expression of this gene is associated with decreased apoptosis, increased cell motility, and cancer progression. There is an antisense transcript that overlaps on the opposite strand with this gene locus. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2012],\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Synthesized peptide derived from human AL1L1 AA range: 512-562\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eTarget: AL1L1\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: This antibody detects endogenous levels of AL1L1 at Human\/Mouse\/Rat\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB 1：500-2000\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml,\u003c\/p\u003e\n\n\u003cp\u003eFormlation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eExpression: Highly expressed in liver, pancreas and kidney,\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 99kD\u003c\/p\u003e\n\n\u003cp\u003eFields: One carbon pool by folate, Metabolic pathways\u003c\/p\u003e\n\n\u003cp\u003eFunction: Catalytic Activity: 10-formyltetrahydrofolate + NADP(+) + H(2)O = tetrahydrofolate + CO(2) + NADPH\u003cbr\u003e\nSimilarity: Belongs to the aldehyde dehydrogenase family\u003cbr\u003e\nSimilarity: Contains 1 acyl carrier domain\u003cbr\u003e\nSimilarity: In the C-terminal section, belongs to the aldehyde dehydrogenase family. ALDH1L subfamily\u003cbr\u003e\nSimilarity: In the N-terminal section, belongs to the GART family\u003c\/p\u003e\n\n\n\u003cp\u003eSubcellular Location: Cytoplasm, cytosol\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: -20°C\/1 year\u003c\/p\u003e\n\n\u003cp\u003eGene Name: ALDH1L1 FTHFD\u003c\/p\u003e\n\n\u003cp\u003eProtein Name: AL1L1\u003c\/p\u003e\n\n\u003cp\u003eMouse Gene ID: 107747\u003c\/p\u003e\n\n\u003cp\u003eMouse SwissProt Number: Q8R0Y6\u003c\/p\u003e\n\n\u003cp\u003eRat Gene ID: 64392\u003c\/p\u003e\n\n\u003cp\u003eRat SwissProt Number: P28037\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ELK Biotechnology","offers":[{"title":"50μL","offer_id":46315831197875,"sku":"ES18410-50","price":186.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":46315831230643,"sku":"ES18410-100","price":372.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/elk_antibodies.jpg?v=1793190497","url":"https:\/\/afsbio.com\/products\/al1l1-rabbit-polyclonal-antibody-es18410","provider":"AFSBio Inc.","version":"1.0","type":"link"}